R
Ryan Christensen
Researcher at Yale University
Publications - 12
Citations - 843
Ryan Christensen is an academic researcher from Yale University. The author has contributed to research in topics: Light sheet fluorescence microscopy & Microscope. The author has an hindex of 9, co-authored 12 publications receiving 729 citations. Previous affiliations of Ryan Christensen include Brigham Young University & National Institutes of Health.
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Journal ArticleDOI
Inverted selective plane illumination microscopy (iSPIM) enables coupled cell identity lineaging and neurodevelopmental imaging in Caenorhabditis elegans
Yicong Wu,Alireza Ghitani,Ryan Christensen,Anthony Santella,Zhuo Du,Gary Rondeau,Zhirong Bao,Daniel A. Colón-Ramos,Hari Shroff +8 more
TL;DR: It is found that canal-associated neurons use somal translocation and amoeboid movement as they migrate to their final position in the embryo, and axon guidance and growth cone dynamics as neurons circumnavigate the nerve ring and reach their targets in the embryos are visualized.
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Spatially isotropic four-dimensional imaging with dual-view plane illumination microscopy
Yicong Wu,Peter Wawrzusin,Justin Senseney,Robert S. Fischer,Ryan Christensen,Anthony Santella,Andrew York,Peter Winter,Clare M. Waterman,Zhirong Bao,Daniel A. Colón-Ramos,Matthew McAuliffe,Hari Shroff +12 more
TL;DR: A dual-view, plane illumination microscope with improved spatiotemporal resolution is developed by switching illumination and detection between two perpendicular objectives in an alternating duty cycle to study biological systems that require high-speed volumetric visualization and/or low photobleaching.
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Synapse Location during Growth Depends on Glia Location
TL;DR: The findings indicate that CIMA-1 antagonizes the FGF receptor (FGFR), and does so most likely by inhibiting FGFR's role in epidermal-glia adhesion rather than signaling.
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A conserved PTEN/FOXO pathway regulates neuronal morphology during C. elegans development
TL;DR: DAF-18 modulates the PI3K signaling pathway to activate DAF-16/FOXO and promote developmental neurite outgrowth during development in Caenorhabditis elegans, providing a novel mechanism by which the conserved PI3k signaling pathway regulates neuronal cell morphology during development through FOXO.
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Reflective imaging improves spatiotemporal resolution and collection efficiency in light sheet microscopy.
Yicong Wu,Abhishek Kumar,Corey Smith,Evan L. Ardiel,Panagiotis Chandris,Ryan Christensen,Ivan Rey-Suarez,Ivan Rey-Suarez,Min Guo,Harshad D. Vishwasrao,Jiji Chen,Jianyong Tang,Arpita Upadhyaya,Patrick J. La Riviere,Patrick J. La Riviere,Hari Shroff +15 more
TL;DR: Reflective coverslips are used to obtain multiple sample views simultaneously, improving the speed of acquisition and resolution compared to dual-view selective plane illumination microscopy.