S
S. Prabu Seenivasan
Researcher at Indian Council of Medical Research
Publications - 5
Citations - 227
S. Prabu Seenivasan is an academic researcher from Indian Council of Medical Research. The author has contributed to research in topics: Antimycobacterial & Quantitative structure–activity relationship. The author has an hindex of 4, co-authored 5 publications receiving 206 citations.
Papers
More filters
Journal ArticleDOI
Synthesis, antimycobacterial activity evaluation, and QSAR studies of chalcone derivatives.
TL;DR: In order to develop relatively small molecules as antimycobacterial agents, twenty-five chalcones were synthesized, their activity was evaluated, and quantitative structure-activity relationship (QSAR) was developed.
Journal ArticleDOI
Synthesis of quinoline coupled [1,2,3]-triazoles as a promising class of anti-tuberculosis agents
TL;DR: The efficiency and fidelity of the Cu(I)-catalyzed azide-alkyne reaction are substantiated by good yields and exclusive formation of the expected 1,4-disubstituted triazole product.
Journal ArticleDOI
Microwave-assisted synthesis, molecular docking and antitubercular activity of 1,2,3,4-tetrahydropyrimidine-5-carbonitrile derivatives.
Sahoo Biswa Mohan,B. Ravi Kumar,Subas Chandra Dinda,Dayanand N. Naik,S. Prabu Seenivasan,Vanaja Kumar,Dharmarajsinh N. Rana,Pathik S. Brahmkshatriya +7 more
TL;DR: Based on bioisosteric similarities with isoniazid, a series of 1,2,3,4-tetrahydropyrimidine-5-carbonitrile derivatives has been designed and some compounds displayed promising antimycobacterial activity comparable or less than the standard drugs isoniaZid and rifampicin.
Journal ArticleDOI
Acetate Kinase (AcK) is Essential for Microbial Growth and Betel-derived Compounds Potentially Target AcK, PhoP and MDR Proteins in M. tuberculosis, V. cholerae and Pathogenic E. coli: An in silico and in vitro Study.
Sandeep Tiwari,Debmalya Barh,Madangchanok Imchen,Eswar Rao,Ranjith Kumavath,S. Prabu Seenivasan,Arun Kumar Jaiswal,Syed Babar Jamal,Vanaja Kumar,Preetam Ghosh,Vasco Azevedo +10 more
TL;DR: It is suggested that, these Piper betel derived compounds may be further tested for developing a novel class of broad-spectrum drugs against various common and MDR pathogens.
Journal ArticleDOI
Microwave‐Assisted Synthesis, Molecular Docking and Antitubercular Activity of 1,2,3,4‐Tetrahydropyrimidine‐5‐carbonitrile Derivatives (IV)
Sahoo Biswa Mohan,B. Ravi Kumar,Subas Chandra Dinda,Dayanand N. Naik,S. Prabu Seenivasan,Vanaja Kumar,Dharmarajsinh N. Rana,Pathik S. Brahmkshatriya +7 more