S
Sabina Pappatà
Researcher at National Research Council
Publications - 148
Citations - 10015
Sabina Pappatà is an academic researcher from National Research Council. The author has contributed to research in topics: Parkinsonism & Dementia. The author has an hindex of 44, co-authored 145 publications receiving 9208 citations. Previous affiliations of Sabina Pappatà include French Institute of Health and Medical Research & United States Atomic Energy Commission.
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Journal ArticleDOI
Diffusion tensor imaging: Concepts and applications
D. Le Bihan,J.-F. Mangin,Cyril Poupon,Chris A. Clark,Sabina Pappatà,Nicolas Molko,Hugues Chabriat +6 more
TL;DR: The concepts behind diffusion tensor imaging are reviewed and potential applications, including fiber tracking in the brain, which, in combination with functional MRI, might open a window on the important issue of connectivity.
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Left prefrontal glucose hypometabolism in the depressed state: a confirmation.
Jean-Luc Martinot,Patrick Hardy,A. Feline,J. D. Huret,Bernard Mazoyer,Dominique Attar-Levy,Sabina Pappatà,André Syrota +7 more
TL;DR: The resting-state cerebral metabolic rates for glucose of severely depressed patients were compared, before and after treatment with tricyclic antidepressants, to those of 10 control subjects of similar age by means of positron emission tomography and the fluorodeoxyglucose method.
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Mutation in the SYNJ1 gene associated with autosomal recessive, early-onset Parkinsonism.
Marialuisa Quadri,Mingyan Fang,Marina Picillo,Simone Olgiati,Guido J. Breedveld,Josja Graafland,Bin Wu,Fengping Xu,Roberto Erro,Marianna Amboni,Sabina Pappatà,Mario Quarantelli,Grazia Annesi,Aldo Quattrone,Hsin F. Chien,Egberto Reis Barbosa,Ben A. Oostra,Paolo Barone,Jun Wang,Vincenzo Bonifati +19 more
TL;DR: The identification of a SYNJ1 homozygous mutation segregating with disease in an Italian consanguineous family with Parkinsonism, dystonia, and cognitive deterioration is reported, delineating a novel form of human Mendelian Parkinsonism and providing further evidence for abnormal synaptic vesicle recycling as a central theme in the pathogenesis.
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Obsessive‐compulsive disorder: a clinical, neuropsychological and positron emission tomography study
Jean-Luc Martinot,J F Allilaire,Bernard Mazoyer,E. Hantouche,J. D. Huret,F. Legaut-Demare,A. G. Deslauriers,Patrick Hardy,Sabina Pappatà,J. C. Baron,A. Syrota +10 more
TL;DR: Results suggest, in OCS, a modification of the general activating systems of cortical function and a relationship between the lateral prefrontal rCMRglu decrease and a selective attention deficit.
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Thalamic microglial activation in ischemic stroke detected in vivo by PET and [11C]PK11195
Sabina Pappatà,M. Levasseur,Roger N. Gunn,Ralph Myers,Christian Crouzel,André Syrota,Terry Jones,Georg W. Kreutzberg,Richard B. Banati +8 more
TL;DR: A persistent increase in [11C]PK11195 binding suggests active, long-term thalamic microstructural changes after corticothalamic connection damage, and activation of microglia in degenerating projection areas remote from the primary lesion.