S
Sabine Molik
Researcher at University of Marburg
Publications - 8
Citations - 1158
Sabine Molik is an academic researcher from University of Marburg. The author has contributed to research in topics: Glutaredoxin & Iron–sulfur cluster. The author has an hindex of 6, co-authored 8 publications receiving 1064 citations.
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Journal ArticleDOI
The role of mitochondria in cellular iron–sulfur protein biogenesis and iron metabolism ☆
Roland Lill,Bastian Hoffmann,Sabine Molik,Antonio J. Pierik,Nicole Rietzschel,Oliver Stehling,Marta A. Uzarska,Holger Webert,Claudia Wilbrecht,Ulrich Mühlenhoff +9 more
TL;DR: Fe/S protein biogenesis and cellular iron metabolism are tightly linked to coordinate iron supply and utilization.
Journal ArticleDOI
Cytosolic monothiol glutaredoxins function in intracellular iron sensing and trafficking via their bound iron-sulfur cluster
Ulrich Mühlenhoff,Sabine Molik,José R. Godoy,Marta A. Uzarska,Nadine Richter,Andreas Seubert,Yan Zhang,JoAnne Stubbe,Fabien Pierrel,Enrique Herrero,Christopher Horst Lillig,Roland Lill +11 more
TL;DR: In this article, the authors identify an essential function of the conserved cytosolic monothiol glutaredoxins Grx3 and Grx4 in intracellular iron trafficking and sensing.
Journal ArticleDOI
Localization and functionality of microsporidian iron–sulphur cluster assembly proteins
Alina V. Goldberg,Sabine Molik,Anastasios D. Tsaousis,Karina Neumann,Grit Kuhnke,Frédéric Delbac,Christian P. Vivarès,Robert P. Hirt,Roland Lill,T. Martin Embley +9 more
TL;DR: The essential biosynthetic process of Fe–S protein assembly as a key function of microsporidian mitosomes is identified.
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The effects of mitochondrial iron homeostasis on cofactor specificity of superoxide dismutase 2.
Mei Yang,Paul A. Cobine,Sabine Molik,Amornrat Naranuntarat,Roland Lill,Dennis R. Winge,Valeria C. Culotta +6 more
TL;DR: A mechanism whereby Saccharomyces cerevisiae manganese superoxide dismutase (SOD2) preferentially bindsManganese over iron based on the differential bioavailability of these ions within mitochondria is described.
Journal ArticleDOI
Evolutionary conservation and in vitro reconstitution of microsporidian iron–sulfur cluster biosynthesis
Sven-A. Freibert,Alina V. Goldberg,Christian Hacker,Sabine Molik,Paul Dean,Tom A. Williams,Sirintra Nakjang,Shaojun Long,Kacper M Sendra,Eckhard Bill,Eva Heinz,Robert P. Hirt,John M. Lucocq,T. Martin Embley,Roland Lill +14 more
TL;DR: It is demonstrated that cristae-deficient mitochondria (mitosomes) of Trachipleistophora hominis are the functional site of iron–sulfur cluster (ISC) assembly, which it is suggested is the essential task of these organelles.