J
JoAnne Stubbe
Researcher at Massachusetts Institute of Technology
Publications - 362
Citations - 23824
JoAnne Stubbe is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Ribonucleotide reductase & Ribonucleotide. The author has an hindex of 79, co-authored 358 publications receiving 22365 citations. Previous affiliations of JoAnne Stubbe include Princeton University & Scripps Research Institute.
Papers
More filters
Journal ArticleDOI
Protein Radicals in Enzyme Catalysis.
Journal ArticleDOI
Mechanisms of bleomycin-induced DNA degradation
JoAnne Stubbe,John W. Kozarich +1 more
Journal ArticleDOI
Radical Initiation in the Class I Ribonucleotide Reductase: Long-Range Proton-Coupled Electron Transfer?
Journal ArticleDOI
Bleomycins: towards better therapeutics
Jingyang Chen,JoAnne Stubbe +1 more
TL;DR: Progress in understanding the mechanisms involved in the therapeutic efficacy of the bleomycins and the unwanted toxicity and elucidation of the biosynthetic pathway of theBleomycin sets the stage for developing a more potent, less toxic therapeutic agent.
Journal ArticleDOI
Phage auxiliary metabolic genes and the redirection of cyanobacterial host carbon metabolism
Luke R. Thompson,Qinglu Zeng,Libusha Kelly,Katherine H. Huang,Alex U. Singer,JoAnne Stubbe,Sallie W. Chisholm +6 more
TL;DR: It is proposed that phage-augmented NADPH production fuels deoxynucleotide biosynthesis for phage replication, and that the selection pressures molding phage genomes involve fitness advantages conferred through mobilization of host energy stores.