S
Sabita Roy
Researcher at University of Miami
Publications - 377
Citations - 10989
Sabita Roy is an academic researcher from University of Miami. The author has contributed to research in topics: Opioid & Receptor. The author has an hindex of 51, co-authored 356 publications receiving 9616 citations. Previous affiliations of Sabita Roy include United States Department of Veterans Affairs & Indian Institute of Chemical Biology.
Papers
More filters
Journal ArticleDOI
Hypoxia-induced microRNA-424 expression in human endothelial cells regulates HIF-α isoforms and promotes angiogenesis
Goutam Ghosh,Indira V. Subramanian,Neeta Adhikari,Xiaoxiao Zhang,Joshi Hemant,David L. Basi,Y S Chandrashekhar,Jennifer L. Hall,Sabita Roy,Yan Zeng,Sundaram Ramakrishnan +10 more
TL;DR: Evidence for what is believed to be a novel mechanism regulating HIF-1α levels in isolated human ECs during hypoxia is provided and results suggest that miR-322/424 plays an important physiological role in post-ischemic vascular remodeling and angiogenesis.
Journal ArticleDOI
Damage-mediated phosphorylation of human p53 threonine 18 through a cascade mediated by a casein 1-like kinase. Effect on Mdm2 binding.
Kazuyasu Sakaguchi,Shin'ichi Saito,Yuichiro Higashimoto,Sabita Roy,Carl W. Anderson,Ettore Appella +5 more
TL;DR: In this article, the authors show that the direct association between a p53 N-terminal peptide and MDM2 is disrupted by phosphorylation of the peptide on Thr18.
Journal ArticleDOI
Vascular Endothelial Growth Factor Signaling in Hypoxia and Inflammation
TL;DR: Understanding the regulation of HIF and its influence on inflammatory response offers unique opportunities for drug development to modulate inflammation and ischemia in pathological conditions.
Journal ArticleDOI
Opioid drug abuse and modulation of immune function: consequences in the susceptibility to opportunistic infections
Sabita Roy,Jana Ninkovic,Santanu Banerjee,Richard Charboneau,Subhas Das,Raini Dutta,Varvara A. Kirchner,Lisa Koodie,Jing Ma,Jingjing Meng,Roderick A. Barke,Roderick A. Barke +11 more
TL;DR: The effects of morphine on innate and adaptive immunity are summarized, the role of the mu opioid receptor in these functions and the signal transduction activated in the process are identified and the clinical relevance of these findings will be discussed.
Journal ArticleDOI
Gut Microbiota Promotes Tumor Growth in Mice by Modulating Immune Response.
Vrishketan Sethi,Saba Kurtom,Mohammad Tarique,Shweta Lavania,Zoe X. Malchiodi,Leonor Hellmund,Li Zhang,Umakant Sharma,Bhuwan Giri,Bharti Garg,Anthony Ferrantella,Selwyn M. Vickers,Sulagna Banerjee,Rajinder Dawra,Sabita Roy,Sundaram Ramakrishnan,Ashok K. Saluja,Vikas Dudeja +17 more
TL;DR: The results suggest that gut microbiome modulation could emerge as a novel immunotherapeutic strategy and reduce tumor burden in pancreatic cancer, colon cancer, and melanoma models.