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Saleh A. Al-Farraj

Researcher at King Saud University

Publications -  220
Citations -  3163

Saleh A. Al-Farraj is an academic researcher from King Saud University. The author has contributed to research in topics: Biology & Phylogenetic tree. The author has an hindex of 24, co-authored 193 publications receiving 2171 citations.

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Phylogenetic analysis and taxonomic distinction of six genera of pathogenic scuticociliates (Protozoa, Ciliophora) inferred from small-subunit rRNA gene sequences

TL;DR: This study sequenced the small-subunit rRNA gene of six species of scuticociliates, Uronemella parafilificum, Metanophrys sinensis, Parauronema longum, Cohnilembus verminus, Porpostoma notata and Ancistrum crassum, the last two of which have not been studied previously using molecular analyses.
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In-silico protein-ligand docking studies against the estrogen protein of breast cancer using pharmacophore based virtual screening approaches.

TL;DR: The potent lead molecule binding mode, residue-interaction patterns and docking energy were examined by molecular docking and binding free energy studies, and the 3ERT complex structural stability and dynamic behavior were monitored by molecular dynamics analysis.
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Molecular interaction analysis of Sulawesi propolis compounds with SARS-CoV-2 main protease as preliminary study for COVID-19 drug discovery

TL;DR: Two compounds, namely glyasperin A and broussoflavonol F, are potential drug candidates for COVID-19 based on their binding affinity and ability to interact with His41 and Cys145 as catalytic sites and displayed favorable interaction profiles with SARS-CoV-2 main protease.
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Further analyses on the phylogeny of the subclass Scuticociliatia (Protozoa, Ciliophora) based on both nuclear and mitochondrial data.

TL;DR: 72 new sequences are characterized, including 40 mitochondrial cytochrome oxidase c subunit I (COI) sequences, 29 mitochondrial small sub unit ribosomal DNA sequences and three small subunit ribosome DNA sequences from 47 isolates of 44 morphospecies are characterized and mitochondrial genes support the monophyly of the order Philasterida.