S
Salman Ahmad Mustfa
Researcher at Manipal University
Publications - 8
Citations - 67
Salman Ahmad Mustfa is an academic researcher from Manipal University. The author has contributed to research in topics: Biology & Transfection. The author has an hindex of 2, co-authored 2 publications receiving 26 citations.
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Journal ArticleDOI
SUMOylation pathway alteration coupled with downregulation of SUMO E2 enzyme at mucosal epithelium modulates inflammation in inflammatory bowel disease.
Salman Ahmad Mustfa,M. P. Singh,Aamir Suhail,Gayatree Mohapatra,Smriti Verma,Debangana Chakravorty,Sarika Rana,Ritika Rampal,Atika Dhar,Sudipto Saha,Vineet Ahuja,C. V. Srikanth +11 more
TL;DR: An important and previously undescribed role for the SUMOylation pathway involving Ubc9 and Akt1 in modulation of epithelial inflammatory signalling in IBD is revealed.
Journal ArticleDOI
A nanogel based oral gene delivery system targeting SUMOylation machinery to combat gut inflammation
Prabhu Srinivas Yavvari,Priyanka Verma,Salman Ahmad Mustfa,Sanjay Pal,Sandeep Kumar,Anand Kumar Awasthi,Vineet Ahuja,C. V. Srikanth,Aasheesh Srivastava,Avinash Bajaj +9 more
TL;DR: This study presents engineering of orally deliverable nanogels that can target SUMOylation machinery to combat gut inflammation with very high efficacy and shows that plasmid delivery using TAC6-derived nanogel diminished gut inflammation in a murine colitis model.
Journal ArticleDOI
Nanoneedles Induce Targeted siRNA Silencing of p16 in the Human Corneal Endothelium
Eleonora Maurizi,Davide A. Martella,Davide Schiroli,Alessia Merra,Salman Ahmad Mustfa,Graziella Pellegrini,C. Macaluso,Ciro Chiappini +7 more
TL;DR: SiRNA nanoinjection targeting the human corneal endothelium is nontoxic ex vivo, and silences p16 in transfected cells, indicating that nanoin injection can support targeted RNA interference therapy for the treatment of endothelial Corneal dysfunction.
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Innate Immune Response and Inflammasome Activation During SARS-CoV-2 Infection
Mohammad Islamuddin,Salman Ahmad Mustfa,Shehla Nasar Mir Najib Ullah,Usmaan Omer,Kentaro Kato,Shama Parveen +5 more
TL;DR: In this article , the authors focus on the innate immune response to SARS-CoV-2 infection and the virus' evasion of the immune system by escaping recognition or inhibiting the production of an antiviral state.
Journal ArticleDOI
Bidirectional regulation between AP-1 and SUMO genes modulates inflammatory signalling during Salmonella infection.
Pharvendra Kumar,Amarendranath Soory,Salman Ahmad Mustfa,Dipanka Tanu Sarmah,Himadri Devvanshi,Samrat Chatterjee,Guillaume Bossis,Girish S. Ratnaparkhi,C. V. Srikanth +8 more
TL;DR: Overall, the data point towards existence of a bidirectional cross-talk between c-Fos and the SUMO pathway and highlighting its importance in AP-1 function relevant to STm infection and beyond.