Sandeep Kumar

TL;DR: CAT-Gel provides a new coordinatively assembled biocompatible scaffold for localized delivery of chemotherapeutic drugs and results in synergistic therapeutic effect with increased median survival against murine lung and breast cancer models.

TL;DR: This review maps out recent advancements in engineering of low molecular weight hydrogels derived from amino acid, fatty acyl, steroidal lipid and drug conjugated amphiphilic scaffolds in terms of biocompatibility, therapeutic potential and challenges associated with existing molecular hydrogel for cancer therapy.

TL;DR: The chemistry of bile acids, bile acid mediated cellular signaling processes, their role in GI cancer progression, and therapeutic potential of synthetic bile Acid derivatives for cancer therapy are discussed.

TL;DR: It is demonstrated that, in addition to a direct mechanism of action against Mycobacterium tuberculosis, 5NP also modulates the host machinery to kill intracellular pathogens.

TL;DR: Results demonstrate that CAPs, as potential broad-spectrum antimicrobials, can effectively clear the frequently encountered polymicrobial infections and can be fine-tuned further for future applications.