S
Samuel Godar
Researcher at University of Vienna
Publications - 9
Citations - 1694
Samuel Godar is an academic researcher from University of Vienna. The author has contributed to research in topics: Cell & Plasminogen activator. The author has an hindex of 9, co-authored 9 publications receiving 1630 citations. Previous affiliations of Samuel Godar include Massachusetts Institute of Technology.
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Journal ArticleDOI
αLβ2 Integrin/LFA-1 Binding to ICAM-1 Induced by Cytohesin-1, a Cytoplasmic Regulatory Molecule
Waldemar Kolanus,Wolfgang Nagel,Britta Schiller,Lutz Zeitlmann,Samuel Godar,Hannes Stockinger,Brian Seed +6 more
TL;DR: A protein is described, cytohesin-1, which specifically interacts with the intracellular portion of the integrin beta 2 chain (CD18), which shows homology to the yeast SEC7 gene product and bears a pleckstrin homology (PH) domain.
Journal ArticleDOI
Growth-Inhibitory and Tumor- Suppressive Functions of p53 Depend on Its Repression of CD44 Expression
Samuel Godar,Tan A. Ince,Tan A. Ince,George W. Bell,David M. Feldser,Joana Liu Donaher,Jonas Bergh,Anne Liu,Kevin Miu,Randolph S. Watnick,Ferenc Reinhardt,Sandra S. McAllister,Tyler Jacks,Robert A. Weinberg +13 more
TL;DR: The data indicate that CD44 is a key tumor-promoting agent in transformed tumor cells lacking p53 function and suggest that the derepression of CD44 resulting from inactivation of p53 can potentially aid the survival of immortalized, premalignant cells.
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Transformation of Different Human Breast Epithelial Cell Types Leads to Distinct Tumor Phenotypes
Tan A. Ince,Andrea L. Richardson,Andrea L. Richardson,George W. Bell,Maki Saitoh,Samuel Godar,Antoine E. Karnoub,James Dirk Iglehart,Robert A. Weinberg +8 more
TL;DR: Compared tumors derived from two different normal human mammary epithelial cell populations, one of which was isolated using a new culture medium, found that the pre-existing differences between BPECs and HMECs strongly influence the phenotypes of their transformed derivatives.
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M6P/IGFII‐receptor complexes urokinase receptor and plasminogen for activation of transforming growth factor‐β1
TL;DR: It is shown that the mannose‐6‐phosphate/insulin‐like growth factor II‐receptor (M6P/IGFII‐R) and uPA‐R suggests a potential mechanism for the generation of TGF‐β1 by cells.
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Acquisition of host cell-surface-derived molecules by HIV-1
Ines Frank,Heribert Stoiber,Samuel Godar,Hannes Stockinger,Franz Steindl,Hermann Katinger,Manfred P. Dierich +6 more
TL;DR: Depending on the cell type used for virus propagation, different cell‐membrane molecules were found on the virus surface reflecting the corresponding cell type, and the uptake of these molecules was selective to a certain degree.