S
Samuel I. Stupp
Researcher at Northwestern University
Publications - 587
Citations - 54611
Samuel I. Stupp is an academic researcher from Northwestern University. The author has contributed to research in topics: Peptide amphiphile & Supramolecular chemistry. The author has an hindex of 109, co-authored 560 publications receiving 49166 citations. Previous affiliations of Samuel I. Stupp include Urbana University & Max Planck Society.
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Journal ArticleDOI
A self-assembled nanofiber catalyst for ester hydrolysis
Mustafa O. Guler,Samuel I. Stupp +1 more
TL;DR: In this paper, a self-assembling peptide amphiphiles (PAs) were synthesized in order to form high-aspect-ratio nanofibers with internal order that can present imidazolyl groups capable of ester hydrolysis.
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Controlled release of dexamethasone from peptide nanofiber gels to modulate inflammatory response.
TL;DR: The use of Dex-PA could facilitate localized anti-inflammatory activity as a component of biomaterials designed for various applications in regenerative medicine and could specifically be a useful module for PA-based therapies.
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Supramolecular crafting of cell adhesion
Hannah Storrie,Mustafa O. Guler,Suha Naffar Abu-Amara,Tova Volberg,Mukti S. Rao,Benjamin Geiger,Samuel I. Stupp +6 more
TL;DR: Self-assembling supramolecular nanofibers that display the cell adhesion ligand RGDS at van der Waals density to cells are used and it is found that branched architectures of the monomers and the consequent lower packing efficiency and additional space for epitope motion improves signaling forcell adhesion, spreading, and migration.
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Tunable mechanics of peptide nanofiber gels.
TL;DR: The ability to modify how self- assembled fibrillar networks respond to deformations is important in developing self-assembled gels that can resist and recover from the large deformations that these gels encounter while serving as synthetic cell scaffolds in vivo.
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Synthesis of Two-Dimensional Polymers
TL;DR: Nonlinear optical experiments reveal that solid films containing the 2D polymers form structures that are thermally and temporally more stable than those containing analogous 1DPolymers, suggesting that the transformation of common polymers from a 1D to a 2D architecture may produce generations of organic materials with improved properties.