S
Sandeep V. Pandit
Researcher at University of Michigan
Publications - 50
Citations - 4286
Sandeep V. Pandit is an academic researcher from University of Michigan. The author has contributed to research in topics: Repolarization & Atrial fibrillation. The author has an hindex of 23, co-authored 48 publications receiving 3901 citations. Previous affiliations of Sandeep V. Pandit include University of Tennessee Health Science Center & State University of New York Upstate Medical University.
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Journal ArticleDOI
A Novel Form of Short QT Syndrome (SQT3) Is Caused by a Mutation in the KCNJ2 Gene
Silvia G. Priori,Sandeep V. Pandit,Ilaria Rivolta,Omer Berenfeld,Elena Ronchetti,Amit S. Dhamoon,Carlo Napolitano,Justus M.B. Anumonwo,Marina Raffaele di Barletta,Smitha Gudapakkam,Giuliano Bosi,Marco Stramba-Badiale,José Jalife +12 more
TL;DR: Computer simulations predict a steeper steady-state restitution curve for the D172N and WT/D172N mutation, compared with WT or to HERG or KvLQT1 mutations, which may predispose SQT3 patients to a greater risk of reentrant arrhythmias.
Journal ArticleDOI
Mechanisms of Wave Fractionation at Boundaries of High-Frequency Excitation in the Posterior Left Atrium of the Isolated Sheep Heart During Atrial Fibrillation
Jérôme Kalifa,Kazuhiko Tanaka,Alexey V. Zaitsev,Mark Warren,Ravi Vaidyanathan,David S. Auerbach,Sandeep V. Pandit,Karen L. Vikstrom,Robert Ploutz-Snyder,Arkadzi Talkachou,Felipe Atienza,Gerard M. Guiraudon,José Jalife,Omer Berenfeld +13 more
TL;DR: During stable AF, the PLA harbors regular, fast, and highly organized activity; the outer limit of the DFmax domain is the area where the most propagation pattern variability and fractionated activity occur.
Journal ArticleDOI
Bone marrow adipose tissue is an endocrine organ that contributes to increased circulating adiponectin during caloric restriction
William P. Cawthorn,Erica L. Scheller,Brian S. Learman,Sebastian D. Parlee,Becky R. Simon,Hiroyuki Mori,Xiaomin Ning,Adam J. Bree,Benjamin Schell,David T. Broome,Sandra S. Soliman,Jenifer L. DelProposto,Carey N. Lumeng,Aditi Mitra,Sandeep V. Pandit,Katherine A. Gallagher,Joshua D. Miller,Venkatesh Krishnan,Susanta K. Hui,Miriam A. Bredella,Pouneh K. Fazeli,Anne Klibanski,Mark C. Horowitz,Clifford J. Rosen,Ormond A. MacDougald +24 more
TL;DR: It is revealed that both MAT and serum adiponectin increase during cancer therapy in humans, and these observations identify MAT as an endocrine organ that contributes significantly to increased serum adip onectin during CR and perhaps in other adverse states.
Journal ArticleDOI
Rotors and the Dynamics of Cardiac Fibrillation
Sandeep V. Pandit,José Jalife +1 more
TL;DR: Examination of recent evidence suggesting that rotors are critical in sustaining both atrial and ventricular fibrillation in the human heart and its implications for treatment with radiofrequency ablation is examined.
Journal ArticleDOI
A Mathematical Model of Action Potential Heterogeneity in Adult Rat Left Ventricular Myocytes
TL;DR: Simulation results support the hypothesis that the smaller density and the slower reactivation kinetics of the Ca(2+)-independent transient outward K(+) current (I(t)) in the endocardial myocytes can account for the longer action potential duration (APD), and more prominent rate dependence in that cell type.