S
Sandra Haider
Researcher at Medical University of Vienna
Publications - 83
Citations - 2511
Sandra Haider is an academic researcher from Medical University of Vienna. The author has contributed to research in topics: Trophoblast & Medicine. The author has an hindex of 22, co-authored 69 publications receiving 1540 citations.
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Journal ArticleDOI
Human placenta and trophoblast development: key molecular mechanisms and model systems.
TL;DR: The role of the developmental pathways Wingless and Notch, controlling trophoblast stemness/differentiation and formation of invasive trophoplast progenitors, respectively are discussed.
Journal ArticleDOI
Self-Renewing Trophoblast Organoids Recapitulate the Developmental Program of the Early Human Placenta
Sandra Haider,Gudrun Meinhardt,Leila Saleh,Viktoria Kunihs,Magdalena Gamperl,Ulrich Kaindl,Adolf Ellinger,Thomas R Burkard,Christian Fiala,Jürgen Pollheimer,Sasha Mendjan,Paulina A. Latos,Martin Knöfler +12 more
TL;DR: Long-term expanding organoid cultures are established that grow and differentiate under defined culture conditions, allowing future human placental disease modeling.
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Effects of a Home-Based and Volunteer-Administered Physical Training, Nutritional, and Social Support Program on Malnutrition and Frailty in Older Persons: A Randomized Controlled Trial.
TL;DR: The results indicate that a home-based physical training, nutritional, and social support intervention conducted by nonprofessionals is feasible and can help to tackle malnutrition and frailty in older persons living at home.
Journal ArticleDOI
Identification of Novel Trophoblast Invasion-Related Genes: Heme Oxygenase-1 Controls Motility via Peroxisome Proliferator-Activated Receptor γ
Martin Bilban,Peter Haslinger,Johanna Prast,Florian Klinglmüller,Thomas Woelfel,Sandra Haider,Alexander Sachs,Leo E. Otterbein,Gernot Desoye,Ursula Hiden,Oswald Wagner,Martin Knöfler +11 more
TL;DR: Gene expression profiling of EVTs and CTBs can be used to unravel novel regulators of cell invasion and identify HO-1 as a negative regulator of trophoblast motility acting via up-regulation of PPARgamma.
Journal ArticleDOI
Notch1 controls development of the extravillous trophoblast lineage in the human placenta.
TL;DR: The results revealed Notch1 as a key factor promoting development of progenitors of the extravillous trophoblast lineage in the human placenta, programming primary trophoblasts into progenitor of the invasive differentiation pathway.