S
Sandra O. Gollnick
Researcher at Roswell Park Cancer Institute
Publications - 71
Citations - 12610
Sandra O. Gollnick is an academic researcher from Roswell Park Cancer Institute. The author has contributed to research in topics: Immune system & Major histocompatibility complex. The author has an hindex of 29, co-authored 68 publications receiving 10850 citations. Previous affiliations of Sandra O. Gollnick include Iowa State University.
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Journal ArticleDOI
Granulocyte-macrophage colony-stimulating factor (GM-CSF) restores allostimulatory function to accessory cells in patients with AIDS.
Zale P. Bernstein,Stephen P. Brooks,Asher Chanan-Khan,Sandra O. Gollnick,Mark J. Gilbert,Kena C. Miller,Thomas B. Tomasi +6 more
TL;DR: The results suggest that the administration of rhGM-CSF can potentially restore allostimulatory function to accessory cells in HIV-infected patients, and this presents a novel way of immune reconstitution.
Journal ArticleDOI
Photopheresis in HIV-1 Infected Patients (Pt) Using Benzoporphyrin Derivative (BPD-MA) Induces Apoptosis in CD4 Cells, Increases Cytolytic T-Cell Activity, Intracellular Expression of Chemokines, and Decreases HIV Infectivity and Viral Load.
Zale P. Bernstein,Thomas J. Dougherty,Stanley A. Schwartz,Sandra O. Gollnick,Carleton C. Stewart,Harold Walder,Madhavan Nair,Supriya D. Mahajan,Adam B. Sumlin,Bernard J. Poiesz +9 more
TL;DR: These studies suggest that ECP augments activity of various arms of the immune system without any significant toxicity and may be effective in controlling HIV replication.
Proceedings ArticleDOI
Photodynamic therapy affects the expression of IL-6 and IL-10 in vivo
TL;DR: It is demonstrated in a BALB/c mouse model that PDT delivered to normal and tumor tissue in vivo causes marked changes in the expression of cytokines interleukin (IL)-6 and IL-10 and it is proposed that the enhancedIL-10 expression plays a role in the observed suppression of cell mediated responses seen following PDT.
Journal ArticleDOI
Photopheresis in HIV-1 Infected Patients Utilizing (Benzoporphyrin Derivative Verteporfin/BPD-MA) and Light.
Zale P. Bernstein,Thomas J. Dougherty,Sandra O. Gollnick,Stanley A. Schwartz,Supriya D. Mahajan,James L. Kepner,Adam B. Sumlin,Carleton C. Stewart,Paul K. Wallace,Harold Walder,Bernard J. Poiesz +10 more
TL;DR: An ex vivo trial utilizing photopheresis with Benzoporphyrin Derivative as the photoactive compound identified the minimum energy levels of light and concentrations of BPD that eradicated both cell-free and cell-associated HIV-1 infectivity without destroying the virus particles or infected leukocytes.
Journal ArticleDOI
Photopheresis in HIV-1 Infected Patients (pt) using Benzoporphyrin Derivative (BPD-MA) Induces Apoptosis in CD4 Cells, Increases Intracellular Expression of Chemokines and Decreases HIV Infectivity and Viral Load.
Zale P. Bernstein,Thomas J. Dougherty,Stanley A. Schwartz,Sandra O. Gollnick,Carleton C. Stewart,Harold Walder,Madhavan Nair,Supriya D. Mahajan,Adam B. Sumlin,Bernard J. Poiesz +9 more
TL;DR: Ex vivo dosing studies suggest that ECP augments activity of various arms of the immune system without any significant toxicity and may be effective in controlling HIV replication.