S
Sandra Odebrecht Vargas Nunes
Researcher at Universidade Estadual de Londrina
Publications - 69
Citations - 3157
Sandra Odebrecht Vargas Nunes is an academic researcher from Universidade Estadual de Londrina. The author has contributed to research in topics: Bipolar disorder & Mood disorders. The author has an hindex of 23, co-authored 62 publications receiving 2582 citations. Previous affiliations of Sandra Odebrecht Vargas Nunes include University of Porto & Chulalongkorn University.
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Stress, depression, the immune system, and cancer
TL;DR: The evidence that various cellular and molecular immunological factors are compromised in chronic stress and depression is overviewed and the clinical implications of these factors in the initiation and progression of cancer are discussed.
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Resveratrol and inflammatory bowel disease: the evidence so far.
TL;DR: The effects of resveratrol should be further investigated by conducting well-designed clinical trials, also taking into account different formulations for the delivery of the bioactive compound.
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The role of oxidative and nitrosative stress in accelerated aging and major depressive disorder.
Pawan Kumar Maurya,Cristiano Noto,Lucas B. Rizzo,Adiel C. Rios,Sandra Odebrecht Vargas Nunes,Décio Sabbatini Barbosa,Sumit Sethi,Maiara Zeni,Rodrigo B. Mansur,Michael Maes,Elisa Brietzke +10 more
TL;DR: Since, aging and MDD share a common biological base in their pathophysiology, the potential therapeutic use of antioxidants and anti-aging molecules in MDD could be promising.
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Shared metabolic and immune-inflammatory, oxidative and nitrosative stress pathways in the metabolic syndrome and mood disorders
Luiz Gustavo Piccoli de Melo,Sandra Odebrecht Vargas Nunes,George M. Anderson,Heber Odebrecht Vargas,Décio Sabbattini Barbosa,Piotr Gałecki,André F. Carvalho,Michael Maes +7 more
TL;DR: Given the high levels of IO&NS and metabolic dysregulation in BD and MDD and the high comorbidity with the atherogenic components of the MetS, mood disorders should be viewed as systemic neuro‐IO&NS‐metabolic disorders.
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Oxidative stress and lowered total antioxidant status are associated with a history of suicide attempts
Heber Odebrecht Vargas,Sandra Odebrecht Vargas Nunes,Márcia Regina Pizzo de Castro,Chiara C. Bortolasci,Décio Sabbatini Barbosa,Helena Kaminami Morimoto,Kamalesh Venugopal,Seetal Dodd,Seetal Dodd,Seetal Dodd,Michael Maes,Michael Berk +11 more
TL;DR: O&NS as well as lowered antioxidant levels may play a role in the pathophysiology of suicidal behavior independently from the effects of depression and smoking, both of which are associated with increased O&NS, and classical suicide predictors, such as years of education and marital status.