S
Sangbum Choi
Researcher at Korea University
Publications - 44
Citations - 486
Sangbum Choi is an academic researcher from Korea University. The author has contributed to research in topics: Population & Accelerated failure time model. The author has an hindex of 10, co-authored 39 publications receiving 424 citations. Previous affiliations of Sangbum Choi include University of Texas Health Science Center at Houston & University of Texas MD Anderson Cancer Center.
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Journal ArticleDOI
Targeted correction and restored function of the CFTR gene in cystic fibrosis induced pluripotent stem cells.
Ana M. Crane,Philipp Kramer,Jacquelin H. Bui,Wook Joon Chung,Xuan Shirley Li,Manuel L. Gonzalez-Garay,Finn Hawkins,Wei Liao,Daniela Mora,Sangbum Choi,Jianbin Wang,Helena C. Sun,David Paschon,Dmitry Guschin,Philip D. Gregory,Darrell N. Kotton,Michael C. Holmes,Eric J. Sorscher,Brian R. Davis +18 more
TL;DR: An exquisitely sensitive, homology-dependent preference for targeting one CFTR allele versus the other is observed, which resulted in restored expression of the mature CFTR glycoprotein and restoration of CFTR chloride channel function in iPSC-derived epithelial cells.
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Clofarabine, idarubicin, and cytarabine (CIA) as frontline therapy for patients ≤60 years with newly diagnosed acute myeloid leukemia.
Aziz Nazha,Hagop M. Kantarjian,Farhad Ravandi,Xuelin Huang,Sangbum Choi,Guillermo Garcia-Manero,Elias Jabbour,Gautam Borthakur,Tapan M. Kadia,Marina Konopleva,Jorge E. Cortes,Alessandra Ferrajoli,Steve Kornblau,Naval Daver,Naveen Pemmaraju,Michael Andreeff,Zeev Estrov,Min Du,Mark Brandt,Stefan Faderl +19 more
TL;DR: CIA is an effective and safe therapy for patients ≤60 years with newly diagnosed AML and retained its favorable impact on OS compared to IA, in multivariate analysis.
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VcR-CVAD induction chemotherapy followed by maintenance rituximab in mantle cell lymphoma: a Wisconsin Oncology Network study
Julie E. Chang,Christopher Peterson,Sangbum Choi,Jens C. Eickhoff,KyungMann Kim,David T. Yang,Leslie A. Gilbert,Eric S. Rogers,Jae Werndli,Michael S. Huie,Thomas McFarland,Michael Volk,Jules H. Blank,Natalie S. Callander,Walter L. Longo,Brad S. Kahl +15 more
TL;DR: The observed 3‐year PFS and OS with VcR‐CVAD in MCL were comparable to reported outcomes with more intensive regimens, and a cooperative group trial (E1405) is attempting to replicate these promising results.
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Early Fibrinolysis Associated with Hemorrhagic Progression Following Traumatic Brain Injury.
Jay Karri,Jessica C. Cardenas,Nena Matijevic,Yao Wei Wang,Sangbum Choi,Liang Zhu,Bryan A. Cotton,Ryan S. Kitagawa,John B. Holcomb,Charles E. Wade +9 more
TL;DR: The findings support a relationship between markers of fibrinolysis in polytrauma patients with severe TBI and PHI, warranting further investigation into the potential for novel, predictive biomarkers.
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A two‐stage approach for dynamic prediction of time‐to‐event distributions
TL;DR: Simulation studies show that the proposed approach achieves stable estimation of biomarker effects over time, has good predictive performance, and is robust against model misspecification.