S
Sankar Bhattacharyya
Researcher at Translational Health Science and Technology Institute
Publications - 41
Citations - 1031
Sankar Bhattacharyya is an academic researcher from Translational Health Science and Technology Institute. The author has contributed to research in topics: RNA & Unfolded protein response. The author has an hindex of 11, co-authored 41 publications receiving 630 citations. Previous affiliations of Sankar Bhattacharyya include Indian Institute of Science.
Papers
More filters
Journal ArticleDOI
Importance of the C-terminal domain of the human GW182 protein TNRC6C for translational repression
TL;DR: It is demonstrated that tethering of each of the human TNRC 6 proteins to a reporter mRNA has a dramatic inhibitory effect on protein synthesis, and the C-terminal part of TNRC6C encompassing the RRM RNA-binding motif as a key effector domain mediating protein synthesis repression by TNRC7C.
Journal ArticleDOI
Platelet activation determines the severity of thrombocytopenia in dengue infection
Amrita Ojha,Dipika Nandi,Harish Batra,Rashi Singhal,Gowtham K. Annarapu,Sankar Bhattacharyya,Tulika Seth,Lalit Dar,Guruprasad R. Medigeshi,Sudhanshu Vrati,Naval K. Vikram,Prasenjit Guchhait +11 more
TL;DR: In vitro data and in vitro data suggest that platelet activation status is an important determinant of thrombocytopenia in dengue infections and a careful strategy of inactivation of platelets may rescue them from rapid destruction during DENV infections.
Journal ArticleDOI
Wuhan to World: The COVID-19 Pandemic.
Ashok Kumar,Ashok Kumar,Rita Singh,Rita Singh,Jaskaran Kaur,Jaskaran Kaur,Sweta Pandey,Sweta Pandey,Vinita Sharma,Vinita Sharma,Lovnish Thakur,Lovnish Thakur,Sangeeta Sati,Shailendra Mani,Shailendra Asthana,Tarun Kumar Sharma,Susmita Chaudhuri,Sankar Bhattacharyya,Niraj Kumar +18 more
TL;DR: In this article, the authors summarized the available knowledge about the pathogen and the disease, COVID-19, and provided a valuable resource to the scientific and clinical community and may help in faster development of the solution to combat the disease.
Journal ArticleDOI
Japanese encephalitis virus replication is negatively regulated by autophagy and occurs on LC3-I- and EDEM1-containing membranes.
Manish Sharma,Sankar Bhattacharyya,Minu Nain,Manpreet Kaur,Vikas Sood,Vishal Gupta,Renu Khasa,Malik Zainul Abdin,Sudhanshu Vrati,Manjula Kalia +9 more
TL;DR: It is suggested that while autophagy is primarily antiviral for JEV and might have implications for disease progression and pathogenesis of JEV, nonlipidated LC3 plays an importantAutophagy independent function in the virus life cycle.
Journal ArticleDOI
Japanese encephalitis virus activates autophagy through XBP1 and ATF6 ER stress sensors in neuronal cells.
Manish Sharma,Manish Sharma,Manish Sharma,Sankar Bhattacharyya,Kiran Bala Sharma,Shailendra Chauhan,Suramya Asthana,Suramya Asthana,Malik Zainul Abdin,Sudhanshu Vrati,Manjula Kalia +10 more
TL;DR: It is demonstrated that a crucial link exists between the ER stress pathways and autophagy in virus-infected cells, and that these processes are highly regulated during virus infection.