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Santanu Maji

Researcher at Virginia Commonwealth University

Publications -  15
Citations -  375

Santanu Maji is an academic researcher from Virginia Commonwealth University. The author has contributed to research in topics: Cancer & Metastasis. The author has an hindex of 8, co-authored 13 publications receiving 212 citations. Previous affiliations of Santanu Maji include Manipal University & Nalco Holding Company.

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Book ChapterDOI

Bcl-2 Antiapoptotic Family Proteins and Chemoresistance in Cancer.

TL;DR: The potential role of B cl-2 antiapoptotic proteins in the development of cancer chemoresistance is overviewed and the clinical approaches that use Bcl-2 inhibitors to restore cell death in chemoresistant and recurrent tumors are overviewed.
Journal ArticleDOI

Mcl-1 is an important therapeutic target for oral squamous cell carcinomas

TL;DR: It is reported for the first time that a BH3 mimetic, Sabutoclax, which functions as an inhibitor of all anti-apoptotic Bcl-2 proteins, induced cancer-specific cell death in an Mcl-1-dependent manner through both apoptosis and toxic mitophagy.
Journal ArticleDOI

STAT3- and GSK3β-mediated Mcl-1 regulation modulates TPF resistance in oral squamous cell carcinoma.

TL;DR: In patient-derived xenograft model of advanced stage and chemoresistant OSCC tumor, Triptolide restores cisplatin-mediated cell death and facilitates significant reduction of tumor burdens.
Journal ArticleDOI

MDA-9/Syntenin (SDCBP): Novel gene and therapeutic target for cancer metastasis.

TL;DR: An overview of the metastatic process is provided and a unique pro-metastatic gene, melanoma differentiation associated gene-9/Syntenin (MDA-9) also called syndecan binding protein (SDCBP), which is a major contributor to the majority of independent metastatic events is highlighted.
Journal ArticleDOI

Good's buffer derived highly emissive carbon quantum dots: excellent biocompatible anticancer drug carrier

TL;DR: The anticancer drug doxorubicin was successfully loaded on the CQDs and their delivery efficiency to the target cells via in vitro treatment of cancerous cells was explored, which showed a higher killing rate of the cancer cells compared to bare DOX.