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Sarah C. Clarke

Researcher at Papworth Hospital

Publications -  51
Citations -  2809

Sarah C. Clarke is an academic researcher from Papworth Hospital. The author has contributed to research in topics: Percutaneous coronary intervention & Coronary artery disease. The author has an hindex of 15, co-authored 42 publications receiving 2509 citations.

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Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics

TL;DR: These studies show for the first time a technique capable of providing an accurate, noninvasive and rapid diagnosis of coronary heart disease that can be used clinically, either in population screening or to allow effective targeting of treatments such as statins.
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Association Between IVUS Findings and Adverse Outcomes in Patients With Coronary Artery Disease: The VIVA (VH-IVUS in Vulnerable Atherosclerosis) Study

TL;DR: VH-IVUS TCFA was associated with nonrestenotic and total MACE on individual plaque analysis, and noncalcified VHTCFA wasassociated with nonRestenoticand total Mace on whole-patient analysis, demonstrating that VH- IVUS can identify plaques at increased risk of subsequent events.
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Cardiac Remote Ischemic Preconditioning in Coronary Stenting (CRISP Stent) Study A Prospective, Randomized Control Trial

TL;DR: Remote IPC reduces ischemic chest discomfort during PCI, attenuates procedure-related cTnI release, and appears to reduce subsequent cardiovascular events.
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Proton NMR analysis of plasma is a weak predictor of coronary artery disease.

TL;DR: Predicting angiographically defined advanced coronary artery disease with >90% accuracy and specificity using plasma samples from groups of male patients, classified by statin treatment, who had normal coronary arteries (NCAs) or CAD is determined.
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Leukocyte Telomere Length Is Associated With High-Risk Plaques on Virtual Histology Intravascular Ultrasound and Increased Proinflammatory Activity

TL;DR: Shorter LTL is associated with high-risk plaque morphology on virtual histology intravascular ultrasound but not total 3-vessel plaque burden, suggesting that telomere shortening promotes high- risk plaque subtypes by increasing proinflammatory activity.