Michael O'Sullivan

TL;DR: In this paper, the authors describe and synthesize data sets and methodology to quantify the five major components of the global carbon budget and their uncertainties, including emissions from land use and land-use change data and bookkeeping models.

TL;DR: In this article, the authors describe data sets and methodology to quantify the five major components of the global carbon budget and their uncertainties, including emissions from land use and land use change, and show that the difference between the estimated total emissions and the estimated changes in the atmosphere, ocean, and terrestrial biosphere is a measure of imperfect data and understanding of the contemporary carbon cycle.

TL;DR: Findings provide direct evidence that white matter tract disruption occurs in normal aging and would be consistent with the cortical disconnection hypothesis of age-related cognitive decline and provide a plausible structural basis for selective loss of executive functions.

TL;DR: The potential for utilizing pupil diameter to achieve a more comprehensive understanding of the role of the LC–NA system in human cognition is highlighted, with the first demonstration in humans of a fundamental characteristic of animal LC activity: phasic modulation by oddball stimulus relevance.

TL;DR: It is suggested that there is evidence of chronic endothelial dysfunction in cerebral SVD, and endothelial prothrombotic changes may be important in mediating the ischaemic leukoaraiosis phenotype.