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Sarah C. Thomasset
Researcher at University of Leicester
Publications - 11
Citations - 682
Sarah C. Thomasset is an academic researcher from University of Leicester. The author has contributed to research in topics: Cancer & Medicine. The author has an hindex of 6, co-authored 7 publications receiving 633 citations. Previous affiliations of Sarah C. Thomasset include Leicester General Hospital & Leicester Royal Infirmary.
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Journal ArticleDOI
Dietary polyphenolic phytochemicals—promising cancer chemopreventive agents in humans? A review of their clinical properties
Sarah C. Thomasset,David P. Berry,Giuseppe Garcea,Timothy H. Marczylo,William P. Steward,Andreas J. Gescher +5 more
TL;DR: A review of pilot studies and trials with a cancer chemoprevention‐related rationale, in which either healthy individuals or patients with premalignant conditions or cancer received polyphenolic phytochemicals is presented.
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Pilot study of oral anthocyanins for colorectal cancer chemoprevention.
Sarah C. Thomasset,David P. Berry,Hong Cai,Kevin West,Tim Marczylo,Debbie Marsden,Karen Brown,Ashley R. Dennison,Giuseppe Garcea,Andrew S. Miller,David Hemingway,William P. Steward,Andreas J. Gescher +12 more
TL;DR: Repeated administration of bilberry anthocyanins exerts pharmacodynamic effects and generates concentrations of anthOCyanins in humans resembling those seen in ApcMin mice, a model of FAP adenomas sensitive to the chemopreventive properties of anthcyanins.
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Do anthocyanins and anthocyanidins, cancer chemopreventive pigments in the diet, merit development as potential drugs?
Sarah C. Thomasset,Nicole Teller,Hong Cai,Doris Marko,David P. Berry,William P. Steward,Andreas J. Gescher +6 more
TL;DR: In the light of their robust cancer chemopreventive efficacy in experimental models and their superior stability as compared to that of the aglycons, the Anthocyanins seem much more suitable for further drug development than their anthocyanidin counterparts.
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Ablation for Recurrent Hepatocellular Carcinoma: A Systematic Review of Clinical Efficacy and Prognostic Factors
TL;DR: Comparable survival figures from previously published systematic reviews suggest that hepatic resection is the most effective treatment for recurrent HCC, however, ablation can be a safe and effective option for the majority of patients with recurrent disease who are unsuitable for surgery.
Journal ArticleDOI
Determination of anthocyanins in the urine of patients with colorectal liver metastases after administration of bilberry extract
Hong Cai,Sarah C. Thomasset,David P. Berry,Giuseppe Garcea,Karen Brown,William P. Steward,Andreas J. Gescher +6 more
TL;DR: There were more anthocyanins and metabolites in the urine of the patient who received mirtoselect via the stomach than via the jejunum, consistent with information obtained in rodents which suggests the stomach is the predominant site for Anthocyanin absorption.