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Sarah E. Fowler

Researcher at George Washington University

Publications -  39
Citations -  28806

Sarah E. Fowler is an academic researcher from George Washington University. The author has contributed to research in topics: Diabetes mellitus & Metformin. The author has an hindex of 29, co-authored 36 publications receiving 27001 citations. Previous affiliations of Sarah E. Fowler include Henry Ford Hospital.

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Prevention of Diabetes in Women with a History of Gestational Diabetes: Effects of Metformin and Lifestyle Interventions

TL;DR: Progression to diabetes is more common in women with a history of GDM compared with those without GDM history despite equivalent degrees of IGT at baseline, and both intensive lifestyle and metformin are highly effective in delaying or preventing diabetes in Women with IGT and a historyof GDM.
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Impact of intensive lifestyle and metformin therapy on cardiovascular disease risk factors in the diabetes prevention program.

TL;DR: Lifestyle intervention improves CVD risk factor status compared with placebo and metformin therapy and achieved risk factor modifications suggest that longer intervention may reduce CVD event rates.
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Prevention of type 2 diabetes with troglitazone in the Diabetes Prevention Program.

TL;DR: Troglitazone markedly reduced the incidence of diabetes during its limited period of use, but this action did not persist, and whether other thiazolidinedione drugs used for longer periods can safely prevent diabetes remains to be determined.
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Role of insulin secretion and sensitivity in the evolution of type 2 diabetes in the diabetes prevention program: effects of lifestyle intervention and metformin.

TL;DR: Higher insulin secretion and sensitivity at baseline and improvements in response to treatment were associated with lower diabetes risk in the DPP, suggesting the better preventive effectiveness of intensive lifestyle may be due to improved insulin sensitivity concomitant with preservation of beta-cell function.