S
Steven E. Kahn
Researcher at University of Washington
Publications - 514
Citations - 62578
Steven E. Kahn is an academic researcher from University of Washington. The author has contributed to research in topics: Diabetes mellitus & Type 2 diabetes. The author has an hindex of 112, co-authored 470 publications receiving 56902 citations. Previous affiliations of Steven E. Kahn include University of Wisconsin-Madison & George Washington University.
Papers
More filters
Journal ArticleDOI
Mechanisms linking obesity to insulin resistance and type 2 diabetes
TL;DR: In obese individuals, adipose tissue releases increased amounts of non-esterified fatty acids, glycerol, hormones, pro-inflammatory cytokines and other factors that are involved in the development of insulin resistance.
Journal ArticleDOI
Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy.
Steven E. Kahn,Steven M. Haffner,Heise Ma,William H. Herman,Rury R. Holman,Nigel P. Jones,Barbara G. Kravitz,John M. Lachin,O'Neill Mc,Bernard Zinman,Giancarlo Viberti +10 more
TL;DR: The potential risks and benefits, the profile of adverse events, and the costs of these three drugs should all be considered to help inform the choice of pharmacotherapy for patients with type 2 diabetes.
Journal ArticleDOI
Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes.
Rena R. Wing,Paula Bolin,Frederick L. Brancati,George A. Bray,Jeanne M. Clark,Mace Coday,Richard S. Crow,Jeffrey M. Curtis,Caitlin Egan,Mark A. Espeland,Mary Evans,John P. Foreyt,Siran Ghazarian,Edward W. Gregg,Barbara Harrison,Helen P. Hazuda,James O. Hill,Edward S. Horton,S. Van Hubbard,John M. Jakicic,Robert W. Jeffery,Karen C. Johnson,Steven E. Kahn,Abbas E. Kitabchi,William C. Knowler,Cora E. Lewis,Barbara J. Maschak-Carey,Maria G. Montez,Anne Murillo,David M. Nathan,Jennifer Patricio,Anne L. Peters,Xavier Pi-Sunyer,Henry J. Pownall,David M. Reboussin,Judith G. Regensteiner,Amy D. Rickman,Donna H. Ryan,Monika M. Safford,Thomas A. Wadden,Lynne E. Wagenknecht,Delia Smith West,David F. Williamson,Susan Z. Yanovski +43 more
TL;DR: An intensive lifestyle intervention focusing on weight loss did not reduce the rate of cardiovascular events in overweight or obese adults with type 2 diabetes.
Journal ArticleDOI
The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes.
TL;DR: Greater understanding of the relative roles of insulin resistance and beta-cell dysfunction in Type 2 diabetes can anticipate advances in the identification of genes contributing to the development of the disease as well as approaches to the treatment and prevention of Type 1 diabetes.
Journal ArticleDOI
Reduction in Weight and Cardiovascular Disease Risk Factors in Individuals With Type 2 Diabetes: One-Year Results of the Look AHEAD Trial
Mark A. Espeland,Xavier Pi-Sunyer,George L. Blackburn,Frederick L. Brancati,George A. Bray,Renee Bright,Jeanne M. Clark,Jeffrey M. Curtis,John P. Foreyt,Kathryn Graves,Steven M. Haffner,Barbara Harrison,James O. Hill,Edward S. Horton,John M. Jakicic,Robert W. Jeffery,Karen C. Johnson,Steven E. Kahn,David E. Kelley,Abbas E. Kitabchi,William C. Knowler,Cora E. Lewis,Barbara J. Maschak-Carey,Brenda Montgomery,David M. Nathan,Jennifer Patricio,Anne L. Peters,J. Bruce Redmon,Rebecca S. Reeves,Donna H. Ryan,Monika M. Safford,Brent Van Dorsten,Thomas A. Wadden,Lynne E. Wagenknecht,Jacqueline Wesche-Thobaben,Rena R. Wing,Susan Z. Yanovski +36 more
TL;DR: At 1 year, ILI resulted in clinically significant weight loss in people with type 2 diabetes and was associated with improved diabetes control and CVD risk factors and reduced medicine use in ILI versus DSE.