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Sarah Murdoch
Researcher at University of Dundee
Publications - 8
Citations - 480
Sarah Murdoch is an academic researcher from University of Dundee. The author has contributed to research in topics: Staphylococcus aureus & Escherichia coli. The author has an hindex of 6, co-authored 8 publications receiving 382 citations.
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Journal ArticleDOI
The Opportunistic Pathogen Serratia marcescens Utilizes Type VI Secretion To Target Bacterial Competitors
Sarah Murdoch,Katharina Trunk,Grant English,Maximilian J. Fritsch,Ehsan Pourkarimi,Sarah J. Coulthurst +5 more
TL;DR: It is concluded that type VI secretion plays a crucial role in the competitiveness, and thus indirectly the virulence, of S. marcescens and other opportunistic bacterial pathogens.
Journal ArticleDOI
Polybacterial human disease: the ills of social networking.
TL;DR: In vivo models and genomic tools are providing new insights into interbacterial behavior during infection and there is potential to target interbacteria interactions as part of a therapeutic strategy.
Journal ArticleDOI
Novel cyclic di-GMP effectors of the YajQ protein family control bacterial virulence
Shi-Qi An,Delphine L. Caly,Yvonne McCarthy,Sarah Murdoch,Joseph Ward,Melanie Febrer,J. Maxwell Dow,Robert P. Ryan +7 more
TL;DR: Genetic and functional analysis of YajQ family members from the human pathogens Pseudomonas aeruginosa and Stenotrophomonas maltophilia showed that they also specifically bound cyclic di-GMP and contributed to virulence in model systems.
Journal ArticleDOI
A membrane-depolarizing toxin substrate of the Staphylococcus aureus type VII secretion system mediates intraspecies competition.
Fatima R. Ulhuq,Margarida C. Gomes,Margarida C. Gomes,Gina Duggan,Gina Duggan,Manman Guo,Chriselle Mendonca,Grant Buchanan,James D. Chalmers,Zhenping Cao,Holger Kneuper,Sarah Murdoch,Sarah Thomson,Henrik Strahl,Matthias Trost,Matthias Trost,Serge Mostowy,Serge Mostowy,Tracy Palmer +18 more
TL;DR: It is shown that TspA has membrane-depolarizing activity and that S. aureus uses TSpA to inhibit the growth of a bacterial competitor in vivo, and that deletion of tspA leads to increased bacterial clearance.
Journal ArticleDOI
In-vitro antibacterial and anti-encrustation performance of silver-polytetrafluoroethylene nanocomposite coated urinary catheters.
Liyun Wang,Shuai Zhang,R. P. Keatch,George Corner,Ghulam Nabi,Sarah Murdoch,Fordyce A. Davidson,Qi Zhao +7 more
TL;DR: Ag-PTFE coated Foley catheters significantly inhibited bacterial migration and biofilm formation on the external catheter surfaces and exhibited excellent biocompatibility with L929 fibroblast cells.