S
Saranya Chumsri
Researcher at Mayo Clinic
Publications - 117
Citations - 2993
Saranya Chumsri is an academic researcher from Mayo Clinic. The author has contributed to research in topics: Breast cancer & Medicine. The author has an hindex of 24, co-authored 74 publications receiving 2252 citations. Previous affiliations of Saranya Chumsri include University of Maryland Marlene and Stewart Greenebaum Cancer Center & University of Maryland, Baltimore.
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Journal ArticleDOI
Next generation of immune checkpoint therapy in cancer: new developments and challenges
Julian A. Marin-Acevedo,Bhagirathbhai Dholaria,Aixa E. Soyano,Keith L. Knutson,Saranya Chumsri,Yanyan Lou +5 more
TL;DR: A comprehensive review of immune checkpoint pathways involved in cancer immunotherapy is provided, and their mechanisms and the therapeutic interventions currently under investigation in phase I/II clinical trials are discussed.
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miR-200a Regulates SIRT1 Expression and Epithelial to Mesenchymal Transition (EMT)-like Transformation in Mammary Epithelial Cells
TL;DR: It is demonstrated that the class III histone deacetylase silent information regulator 1 (SIRT1), a proposed oncogene in breast cancer, is overexpressed upon EMT-like transformation and that epigenetic silencing of miR-200a contributes at least in part to the overexpression of SIRT1.
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Aromatase, aromatase inhibitors, and breast cancer.
TL;DR: Three aromatase inhibitors (AIs) are now FDA approved and have been shown to be more effective than the antiestrogen tamoxifen and are well tolerated and are now a standard treatment for postmenopausal patients.
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Circulating giant macrophages as a potential biomarker of solid tumors
Daniel L. Adams,Stuart S. Martin,R. Katherine Alpaugh,Monica S. Charpentier,Susan Tsai,Raymond C. Bergan,Irene M. Ogden,William J. Catalona,Saranya Chumsri,Cha-Mei Tang,Massimo Cristofanilli +10 more
TL;DR: Evidence is supplied that this circulating giant cell is a subset of disseminated tumor-associated macrophages capable of binding CTCs in peripheral blood of cancer patients, supporting the hypothesis that disseminated TAMs can be used as a biomarker of advanced disease and suggesting that they have a participatory role in tumor cell migration.
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Cytometric characterization of circulating tumor cells captured by microfiltration and their correlation to the CellSearch(®) CTC test.
Daniel L. Adams,Steingrimur Stefansson,Christian C. Haudenschild,Stuart S. Martin,Monica S. Charpentier,Saranya Chumsri,Massimo Cristofanilli,Cha-Mei Tang,R. Katherine Alpaugh +8 more
TL;DR: An exploratory method comparison study to characterize and compare the CTC subgroups captured from duplicate blood samples from 30 breast and prostate cancer patients using a microfiltration system (CellSieve™) and CellSearch identified a specific CTC morphology which is highly correlative between two distinct capture methods.