Sascha Ferlaino

TL;DR: Flubromazepam appears to have an extremely long elimination half-life of more than 100 h, which means that it could be misused in drug-withdrawal settings or in other circumstances requiring regular drug testing, and may be used indrug-facilitated crimes without being detected.

TL;DR: Subsequent conversion by the short-chain dehydrogenase/reductase (SDR) MdpC into the corresponding 3-hydroxy-3,4-dihydroanthracen-1(2H)-one implies that deoxygenation is the first step in monodictyphenone biosynthesis.

TL;DR: In this paper, the authors described the characterization of pyrazolam (8-bromo-1-methyl-6-pyridin-2-yl-4H-(1,2,4) triazolo(4,3-a)(1, 4)benzodiazepine) using gas chroma-to-graphy-mass spectrometry, liquid chromatography tandem mass spectrometer (LC-MS-MS), liquid chroma tography quadrupole time-of-flight mass spectrametry (LC

TL;DR: The reduction of C=N bonds with good levels of conversion and excellent enantioselectivity by GDH represents a promiscuous catalytic activity of this enzyme.

TL;DR: This facile and robust method developed for 25OHVD3 synthesis is a novel example for the concept of substrate-engineered catalysis and offers an attractive alternative to chemical or O2 /electron-donor-dependent enzymatic procedures.