S
Sebastien Gallien
Researcher at University of Strasbourg
Publications - 62
Citations - 2914
Sebastien Gallien is an academic researcher from University of Strasbourg. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 27, co-authored 44 publications receiving 2550 citations. Previous affiliations of Sebastien Gallien include International Pentecostal Holiness Church & Centre national de la recherche scientifique.
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Targeted Proteomic Quantification on Quadrupole-Orbitrap Mass Spectrometer
TL;DR: The increased quality of quadrupole-orbitrap data has the potential to improve existing protein quantification methods in complex samples and address the pressing demand of systems biology or biomarker evaluation studies.
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Selected reaction monitoring applied to proteomics
TL;DR: O Ongoing developments aiming at increasing multiplexing capabilities of SRM dramatically improve its throughput and extend its field of application to directed or supervised discovery experiments, as well as describing the specificities and the technical aspects of proteomics experiments.
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Parallel reaction monitoring using quadrupole-Orbitrap mass spectrometer: Principle and applications.
TL;DR: Various implementation schemes of parallel reaction monitoring (PRM) are described and their benefits and limitations in terms of quantification performance and confidence in analyte identification are discussed.
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Large-Scale Targeted Proteomics Using Internal Standard Triggered-Parallel Reaction Monitoring (IS-PRM)
TL;DR: The IS-PRM method showed an unprecedented combination of scale and analytical performance, with limits of quantification in the low amol range, and was designed to maximize the effective time devoted to measure the analytes in a time-scheduled targeted experiment.
Journal ArticleDOI
Metabolic diversity among main microorganisms inside an arsenic-rich ecosystem revealed by meta- and proteo-genomics.
Philippe N. Bertin,Audrey Heinrich-Salmeron,Eric Pelletier,Eric Pelletier,Florence Goulhen-Chollet,Florence Arsène-Ploetze,Sebastien Gallien,Béatrice Lauga,Corinne Casiot,Alexandra Calteau,Alexandra Calteau,David Vallenet,David Vallenet,Violaine Bonnefoy,Odile Bruneel,Béatrice Chane-Woon-Ming,Béatrice Chane-Woon-Ming,Jessica Cleiss-Arnold,Robert Duran,Françoise Elbaz-Poulichet,Nuria Fonknechten,Nuria Fonknechten,Ludovic Giloteaux,David Halter,Sandrine Koechler,Marie Marchal,Damien Mornico,Damien Mornico,Christine Schaeffer,Adam Alexander T. Smith,Adam Alexander T. Smith,Alain Van Dorsselaer,Jean Weissenbach,Jean Weissenbach,Claudine Médigue,Claudine Médigue,Denis Le Paslier,Denis Le Paslier +37 more
TL;DR: It is demonstrated here that an acid mine drainage highly contaminated with arsenic is dominated by seven bacterial strains whose genomes were reconstructed, which include two strains belonging to a novel bacterial phylum present in some similar ecosystems, and which was named ‘Candidatus Fodinabacter communificans.