S
Sébastien Guihard
Researcher at University of Strasbourg
Publications - 36
Citations - 253
Sébastien Guihard is an academic researcher from University of Strasbourg. The author has contributed to research in topics: Radiation therapy & Medicine. The author has an hindex of 6, co-authored 28 publications receiving 201 citations.
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Journal ArticleDOI
CD8-alpha T-cell infiltration in human papillomavirus-related oropharyngeal carcinoma correlates with improved patient prognosis.
Alain C. Jung,Sébastien Guihard,Sylvie Krugell,Sonia Ledrappier,Alexandra Brochot,Véronique Dalstein,Sylvie Job,Aurélien de Reyniès,Georges Noël,Bohdan Wasylyk,Christine Clavel,Joseph Abecassis +11 more
TL;DR: The results suggest that an increased cytotoxic T‐cell‐based antitumor immune response is involved in improved prognosis of patients with HPV‐positive tumors.
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MiR-422a promotes loco-regional recurrence by targeting NT5E/CD73 in head and neck squamous cell carcinoma.
Nathalie Bonnin,Emma Armandy,Julien Carras,Sylvain Ferrandon,Priscillia Battiston-Montagne,Marc Aubry,Sébastien Guihard,David Meyronet,David Meyronet,Jean-Philippe Foy,Pierre Saintigny,Sonia Ledrappier,Alain Jung,Ruth Rimokh,Claire Rodriguez-Lafrasse,Delphine Poncet +15 more
TL;DR: It is reported, for the first time, that MiR-422a and its target CD73 are involved in early loco(regional) recurrence of HNSCC tumors and are new targets for personalized medicine.
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The NEDD8 conjugation pathway regulates p53 transcriptional activity and head and neck cancer cell sensitivity to ionizing radiation
Sébastien Guihard,Ludivine Ramolu,Christine Macabre,Bohdan Wasylyk,Georges Noël,Joseph Abecassis,Alain C. Jung +6 more
TL;DR: Results indicate that NAE1/APP-BP1 and NEDDylation are invovled in modulating p53 activity and regulating its role in the response of cells to ionizing radiation.
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Early evaluation predicts pain relief of irradiated bone metastases: a single-center prospective study
Pierre Truntzer,D. Atlani,Marius Pop,Jean-Baptiste Clavier,Sébastien Guihard,C. Schumacher,Georges Noël +6 more
TL;DR: Pain management alone is not enough to improve performance status; further studies are needed to evaluate a more global supportive care approach and the response at d8 is predictive of the response in the first month after treatment.
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Radiothérapie en conditions stéréotaxiques des tumeurs bénignes intracrâniennes
TL;DR: Le traitement des lesions benignes avec une irradiation en conditions stereotaxiques donne des resultats satisfaisants avec peu of complications.