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Seema S. Lakdawala

Researcher at University of Pittsburgh

Publications -  81
Citations -  2846

Seema S. Lakdawala is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Virus & Influenza A virus. The author has an hindex of 22, co-authored 61 publications receiving 1747 citations. Previous affiliations of Seema S. Lakdawala include National Institute for Occupational Safety and Health & National Institutes of Health.

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Journal ArticleDOI

Airborne transmission of respiratory viruses.

TL;DR: In this article, the authors discuss current evidence regarding the transmission of respiratory viruses by aerosols-how they are generated, transported, and deposited, as well as the factors affecting the relative contributions of droplet-spray deposition versus aerosol inhalation as modes of transmission.
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Mechanistic insights into the effect of humidity on airborne influenza virus survival, transmission and incidence.

TL;DR: This perspective article re-evaluate studies of influenza virus survival in aerosols, transmission in animal models and influenza incidence to show that the combination of temperature and RH is equally valid as AH as a predictor, and presents a mechanistic explanation based on droplets evaporation and its impact on droplet physics and chemistry for why RH is more likely than AH to modulate virus survival and transmission.
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Eurasian-origin gene segments contribute to the transmissibility, aerosol release, and morphology of the 2009 pandemic H1N1 influenza virus.

TL;DR: It is demonstrated that the release of influenza viral RNA-containing particles into the air correlates with increased NA activity and the pleomorphic phenotype of the pH1N1 virus is dependent upon the Eurasian-origin gene segments, suggesting a link between transmission and virus morphology.
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Influenza Virus Infectivity Is Retained in Aerosols and Droplets Independent of Relative Humidity.

TL;DR: In contrast to previously published reports, sustained infectivity of aerosolized influenza viruses in respiratory mucus over a wide-range of relative humidity conditions is detected, indicating a risk of airborne transmission in a broad range of environments.