S
Seham A. Elkheshen
Researcher at Future University in Egypt
Publications - 37
Citations - 877
Seham A. Elkheshen is an academic researcher from Future University in Egypt. The author has contributed to research in topics: Drug carrier & PLGA. The author has an hindex of 16, co-authored 34 publications receiving 640 citations. Previous affiliations of Seham A. Elkheshen include University of Rhode Island & King Saud University.
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Journal ArticleDOI
Inclusion complexes of tadalafil with natural and chemically modified beta-cyclodextrins. I: preparation and in-vitro evaluation
TL;DR: The results showed the formation of true inclusion complexes between the drug and both HP-beta-CD and DM- beta-CD using the freeze-drying method at molar ratio of 1:5, which showed superior dissolution enhancement than other methods especially when combined with the Beta-CD derivatives.
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Colloidal (-)-epigallocatechin-3-gallate vesicular systems for prevention and treatment of skin cancer: A comprehensive experimental study with preclinical investigation.
TL;DR: EGCG PEVs succeeded in offering an effective delivery system targeting skin cancer, which is worthy of further experimentation.
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Studying the influence of formulation and process variables on Vancomycin-loaded polymeric nanoparticles as potential carrier for enhanced ophthalmic delivery.
Carol Yousry,Seham A. Elkheshen,Hanan M. El-Laithy,Tamer Essam,Rania H. Fahmy,Rania H. Fahmy +5 more
TL;DR: VCM‐loaded PNPs represent promising carriers with superior achievements for enhanced Vancomycin ophthalmic delivery over the traditional use of commercially available VCM parenteral powder after constitution into a solution by the ophthalmologists.
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Clinical cosmeceutical repurposing of melatonin in androgenic alopecia using nanostructured lipid carriers prepared with antioxidant oils
TL;DR: Melatonin NLCs displayed more clinically desirable results compared to the melatonin solution in AGA patients, manifested by increased hair density and thickness and decreased hair loss.
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Melatonin vitamin C-based nanovesicles for treatment of androgenic alopecia: Design, characterization and clinical appraisal.
Shymaa Hatem,Maha Nasr,Maha Nasr,Noha H. Moftah,Maha H. Ragai,Ahmed S. Geneidi,Seham A. Elkheshen +6 more
TL;DR: It is revealed that melatonin vitamin C‐based aspasomes showed favorable pharmaceutical properties in addition to clinically promising results compared to melatonin solution, manifested by increased hair thickness, density and decreased hair loss, with photographic improvement in most patients.