Journal ArticleDOI
Colloidal (-)-epigallocatechin-3-gallate vesicular systems for prevention and treatment of skin cancer: A comprehensive experimental study with preclinical investigation.
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EGCG PEVs succeeded in offering an effective delivery system targeting skin cancer, which is worthy of further experimentation.About:
This article is published in European Journal of Pharmaceutical Sciences.The article was published on 2019-09-01. It has received 53 citations till now. The article focuses on the topics: Epidermoid carcinoma.read more
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Advancements in liposome technology: Preparation techniques and applications in food, functional foods, and bioactive delivery: A review.
K.K. Ajeeshkumar,Peruvazhipurath Appu Aneesh,Navaneethan Raju,Mathew Suseela,C.N. Ravishankar,Soottawat Benjakul +5 more
TL;DR: In this article, a review of the current techniques and methodologies developed and practiced in liposomal preparation and application in functional foods is presented, including microfluidization, ultrasonication and supercritical fluidic methods.
Journal ArticleDOI
Nanoemulsion as a feasible and biocompatible carrier for ocular delivery of travoprost: Improved pharmacokinetic/pharmacodynamic properties.
TL;DR: Results showed that travoprost nanoemulsions exhibited suitable nanodroplet size, zeta potential, pH, refractive index, controlled release, as well as sufficient stability under accelerated conditions, and it can be suggested that trawler nanoemulsion is a promising ocular delivery system for glaucoma treatment.
Journal ArticleDOI
Ethanol injection technique for liposomes formulation: An insight into development, influencing factors, challenges and applications
TL;DR: In this paper, the authors provide a deeper understanding of the ethanol injection method and the introduced modifications and the parameters influencing the process such as injection velocity, stirring rate, injection hole diameter, lipid concentration, osmolality/pH/viscosity of the aqueous phase, volume of utilized ethanol and its residual amount, dimensions of reaction vessel and type of drug to be loaded.
Journal ArticleDOI
Chitosan nanoparticles making their way to clinical practice: A feasibility study on their topical use for acne treatment.
TL;DR: When clinically tested on patients, nicotinamide nanoparticles displayed 73% reduction in the inflammatory acne lesions compared to untreated areas, hence proving that chitosan nanoparticles can be a clinically sounding option for treatment of skin diseases.
Journal ArticleDOI
Plant-Derived Natural Products in Cancer Research: Extraction, Mechanism of Action, and Drug Formulation.
TL;DR: This review describes the main plant-derived natural products used as anticancer agents and should provide a solid foundation for researchers and physicians to enhance basic and clinical research on developing alternative anticancer therapies.
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Journal ArticleDOI
Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
TL;DR: Using this method, the liped peroxide level in the liver of rats suffering from carbon tetrachloride intoxication was investigated and was in good agreement with previously reported data obtained by measuring diene content.
Book ChapterDOI
Catalase in vitro
TL;DR: In this article, the catalytic activity of catalase has been investigated using ultraviolet (UV) spectrophotometry and Titrimetric methods, which is suitable for comparative studies for large series of measurements.
Journal ArticleDOI
Involvement of the Superoxide Anion Radical in the Autoxidation of Pyrogallol and a Convenient Assay for Superoxide Dismutase
TL;DR: The autoxidation of pyrogallol was investigated in the presence of EDTA in the pH range 7.9–10.6, indicating an almost total dependence on the participation of the superoxide anion radical, O2·−, in the reaction.
Journal ArticleDOI
Levels of glutathione, glutathione reductase and glutathione S-transferase activities in rat lung and liver.
TL;DR: The activities of some glutathione-metabolizing enzymes were observed to be 5-to 60-fold lower in lung tissue than in the liver, and that phenobarbital nor methylcholanthrene had a significant effect on the levels of reduced glutATHione in lung and liver.
Journal ArticleDOI
Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal.
TL;DR: This review focuses on biochemical concepts of lipidPeroxidation, production, metabolism, and signaling mechanisms of two main omega-6 fatty acids lipid peroxidation products: malondialdehyde (MDA) and, in particular, 4-hydroxy-2-nonenal (4-HNE), summarizing not only its physiological and protective function as signaling molecule stimulating gene expression and cell survival, but also its cytotoxic role inhibiting geneexpression and promoting cell death.
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