S
Senthil Kumar K. Sakthivel
Researcher at Centers for Disease Control and Prevention
Publications - 3
Citations - 781
Senthil Kumar K. Sakthivel is an academic researcher from Centers for Disease Control and Prevention. The author has contributed to research in topics: Coronavirus & Virus. The author has an hindex of 3, co-authored 3 publications receiving 564 citations.
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Severe Acute Respiratory Syndrome Coronavirus 2 from Patient with Coronavirus Disease, United States.
Jennifer L Harcourt,Jennifer L Harcourt,Azaibi Tamin,Xiaoyan Lu,Shifaq Kamili,Senthil Kumar K. Sakthivel,Janna Murray,Krista Queen,Ying Tao,Clinton R. Paden,Jing Zhang,Yan Li,Anna Uehara,Haibin Wang,Cynthia S. Goldsmith,Hannah A. Bullock,Lijuan Wang,Brett Whitaker,Brian Lynch,Rashi Gautam,Craig Schindewolf,Kumari G. Lokugamage,Dionna Scharton,Jessica A. Plante,Divya Mirchandani,Steven G. Widen,Krishna Narayanan,Shinji Makino,Thomas G. Ksiazek,Kenneth S. Plante,Scott C. Weaver,Stephen Lindstrom,Suxiang Tong,Suxiang Tong,Vineet D. Menachery,Vineet D. Menachery,Natalie J. Thornburg,Natalie J. Thornburg,Natalie J. Thornburg +38 more
TL;DR: It is found that the virus replicates to high titer in Vero-CCL81 cells and Vero E6 cells in the absence of trypsin, and it is hoped that open access to this reagent will expedite development of medical countermeasures.
Journal ArticleDOI
Real-Time Reverse Transcription-PCR Assay Panel for Middle East Respiratory Syndrome Coronavirus
Xiaoyan Lu,Brett Whitaker,Senthil Kumar K. Sakthivel,Shifaq Kamili,Laura Rose,Luis Lowe,Emad Mohareb,Emad Elassal,Tarek Alsanouri,Aktham Haddadin,Dean D. Erdman +10 more
TL;DR: Two real-time reverse transcription-PCR assays targeting the MERS-CoV nucleocapsid (N) gene were developed and evaluated as a panel with a previously published assay targeting the region upstream of the MSPV envelope gene (upE) for the detection and confirmation of MERS -CoV infection.
Posted ContentDOI
Isolation and characterization of SARS-CoV-2 from the first US COVID-19 patient
Jennifer L Harcourt,Azaibi Tamin,Xiaoyan Lu,Shifaq Kamili,Senthil Kumar K. Sakthivel,Lijuan Wang,Janna Murray,Krista Queen,Brian Lynch,Brett Whitaker,Ying Tao,Clinton R. Paden,Jing Zhang,Yan Li,Anna Uehara,Haibin Wang,Cynthia S. Goldsmith,Hannah A. Bullock,Rashi Gautam,Craig Schindewolf,Kumari G. Lokugamage,Diona Scharton,Jessica A. Plante,Divya Mirchandani,Stephen G. Widen,Krishna Narayanan,Shinji Makino,Thomas G. Ksiazek,Kenneth S. Plante,Scott C. Weaver,Vineet D. Menachery,Natalie J. Thornburg +31 more
TL;DR: The isolation and reagents described here will serve as the US reference strain used in research, drug discovery and vaccine testing, and it is hoped that open access to this important reagent will expedite development of medical countermeasures.