S
Sergio Florez
Researcher at Pennsylvania State University
Publications - 17
Citations - 653
Sergio Florez is an academic researcher from Pennsylvania State University. The author has contributed to research in topics: Transcription factor & Chemistry. The author has an hindex of 11, co-authored 13 publications receiving 555 citations. Previous affiliations of Sergio Florez include University of Iowa & Texas A&M Health Science Center.
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Journal ArticleDOI
Enhanced somatic embryogenesis in Theobroma cacao using the homologous BABY BOOM transcription factor
TL;DR: The use of the transcription factor Baby Boom (BBM) to promote the transition of somatic cacao cells from the vegetative to embryonic state is described to provide validation that TcBBM is an ortholog to AtBBM and has a specific role in both somatic and zygotic embryogenesis.
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The Pitx2:miR-200c/141:noggin pathway regulates Bmp signaling and ameloblast differentiation
Huojun Cao,Andrew H. Jheon,Xiao Li,Zhao Sun,Jianbo Wang,Sergio Florez,Zichao Zhang,Michael T. McManus,Ophir D. Klein,Brad A. Amendt +9 more
TL;DR: In vivo and in vitro studies reveal a multistep transcriptional program involving the Pitx2:miR-200c/141:noggin regulatory pathway that is important in epithelial cell differentiation and tooth development.
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MicroRNAs Play a Critical Role in Tooth Development
Huojun Cao,Jianbo Wang,Xiao Li,Sergio Florez,Z. Huang,Shankar Rengasamy Venugopalan,Satheesh Elangovan,Ziedonis Skobe,Henry C. Margolis,James F. Martin,Brad A. Amendt +10 more
TL;DR: It is demonstrated that tooth development is tightly controlled by microRNAs and that specific micro RNAs regulate tooth epithelial stem cell differentiation.
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MicroRNAs Regulate Pituitary Development, and MicroRNA 26b Specifically Targets Lymphoid Enhancer Factor 1 (Lef-1), Which Modulates Pituitary Transcription Factor 1 (Pit-1) Expression
TL;DR: It is demonstrated that microRNAs are critical for anterior pituitary development and that miR-26b regulatespituitary expression by inhibiting Lef-1 expression and may promote Pit-1 lineage differentiation during pituitsary development.
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Materials Fabrication from Native and Recombinant Thermoplastic Squid Proteins
Abdon Pena-Francesch,Sergio Florez,Huihun Jung,Aswathy Sebastian,Istvan Albert,Wayne R. Curtis,Melik C. Demirel +6 more
TL;DR: The next generation sequencing approach is used to identify protein sequences in a squid ring teeth complex extracted from Loligo vulgaris and the use of recombinant expression is demonstrated in the fabrication of a new generation of thermoplastic materials.