S
Sérgio Henrique Sousa Santos
Researcher at Unimontes
Publications - 11
Citations - 1380
Sérgio Henrique Sousa Santos is an academic researcher from Unimontes. The author has contributed to research in topics: Adipose tissue & Insulin. The author has an hindex of 11, co-authored 11 publications receiving 1208 citations. Previous affiliations of Sérgio Henrique Sousa Santos include Universidade Federal de Minas Gerais & National Institute of Standards and Technology.
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Journal ArticleDOI
Mas Deficiency in FVB/N Mice Produces Marked Changes in Lipid and Glycemic Metabolism
Sérgio Henrique Sousa Santos,Luciana Rodrigues Fernandes,Érica Guilhen Mario,Adaliene Versiani Matos Ferreira,Laura Cristina Jardim Porto,Jaqueline Isaura Alvarez-Leite,Leida Maria Botion,Michael Bader,Natalia Alenina,Robson A.S. Santos +9 more
TL;DR: These results show that Mas deficiency in FVB/N mice leads to dramatic changes in glucose and lipid metabolisms, inducing a metabolic syndrome–like state.
Journal ArticleDOI
Resveratrol attenuates hepatic steatosis in high-fat fed mice by decreasing lipogenesis and inflammation
João Marcus Oliveira Andrade,Alanna Fernandes Paraíso,Marcos Vinícius Macedo de Oliveira,Andréa Maria Eleutério de Barros Lima Martins,João Felício Rodrigues Neto,André Luiz Sena Guimarães,Alfredo Maurício Batista de Paula,Mahboob Qureshi,Sérgio Henrique Sousa Santos +8 more
TL;DR: Treatment with resveratrol improved lipid metabolism, and decreased NAFLD and pro-inflammatory profile in liver of mice with obesity-inducible diets, suggesting an important clinical application of RSV in preventing liver diseases.
Journal ArticleDOI
Adipokines, diabetes and atherosclerosis: an inflammatory association
Leandro Ceotto Freitas Lima,Valdir A. Braga,Maria do Socorro de França Silva,Josiane C. Cruz,Sérgio Henrique Sousa Santos,Matheus M.O. Monteiro,Camille M. Balarini +6 more
TL;DR: The role of the main adipokines in the pathophysiology of diabetes and atherosclerosis is explored, highlighting the therapeutic options that could arise from the manipulation of these signaling pathways both in humans and in translational models.
Journal ArticleDOI
Nuclear sirtuins and inflammatory signaling pathways.
Keila Lopes Mendes,Deborah de Farias Lelis,Sérgio Henrique Sousa Santos,Sérgio Henrique Sousa Santos +3 more
TL;DR: The roles of nuclear sirtuins in inflammatory reactions: SIRT1 has been shown to suppress NF-κb activity, the master regulator of cellular inflammatory response, decrease COX-2 and iNOS production, and increase antioxidant gene expression that suppressed inflammation.
Journal ArticleDOI
Improved Lipid and Glucose Metabolism in Transgenic Rats With Increased Circulating Angiotensin-(1-7)
Sérgio Henrique Sousa Santos,Janaina F Braga,Érica Guilhen Mario,Laura Cristina Jardim Porto,Maria da Glória Rodrigues-Machado,Antonela Murari,Leida Maria Botion,Natalia Alenina,Michael Bader,Robson A.S. Santos +9 more
TL;DR: Results show that increased circulating angiotensin-(1-7) levels lead to prominent changes in glucose and lipid metabolism, including decreased triglycerides and cholesterol levels, despite normal food intake.