V
Valdir A. Braga
Researcher at Federal University of Paraíba
Publications - 127
Citations - 2599
Valdir A. Braga is an academic researcher from Federal University of Paraíba. The author has contributed to research in topics: Baroreflex & Angiotensin II. The author has an hindex of 24, co-authored 120 publications receiving 2098 citations. Previous affiliations of Valdir A. Braga include University of São Paulo & Cornell University.
Papers
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Journal ArticleDOI
Increased sympathetic outflow in juvenile rats submitted to chronic intermittent hypoxia correlates with enhanced expiratory activity
Daniel B. Zoccal,Annabel E. Simms,Leni G.H. Bonagamba,Valdir A. Braga,Anthony E. Pickering,Julian F. R. Paton,Benedito H. Machado +6 more
TL;DR: The data indicate that CIH rats present an altered pattern of central sympathetic–respiratory coupling, with increased tSNA that correlates with enhanced late expiratory discharge in the Abd nerve, that may contribute to the induced hypertension in this experimental model.
Journal ArticleDOI
Adipokines, diabetes and atherosclerosis: an inflammatory association
Leandro Ceotto Freitas Lima,Valdir A. Braga,Maria do Socorro de França Silva,Josiane C. Cruz,Sérgio Henrique Sousa Santos,Matheus M.O. Monteiro,Camille M. Balarini +6 more
TL;DR: The role of the main adipokines in the pathophysiology of diabetes and atherosclerosis is explored, highlighting the therapeutic options that could arise from the manipulation of these signaling pathways both in humans and in translational models.
Journal ArticleDOI
Involvement of l-glutamate and ATP in the neurotransmission of the sympathoexcitatory component of the chemoreflex in the commissural nucleus tractus solitarii of awake rats and in the working heart–brainstem preparation
Valdir A. Braga,Renato N. Soriano,Alex L. Braccialli,Patricia M. De Paula,Leni G.H. Bonagamba,Julian F. R. Paton,Benedito H. Machado +6 more
TL;DR: It is concluded that glutamatergic and purinergic mechanisms are part of the complex neurotransmission system of the sympathoexcitatory component of the chemoreflex at the level of the commissural NTS.
Journal ArticleDOI
Angiotensin-II-induced reactive oxygen species along the SFO-PVN-RVLM pathway: implications in neurogenic hypertension
Valdir A. Braga,Isac Almeida de Medeiros,Thaís P. Ribeiro,Maria S. França-Silva,M S Botelho-Ono,Drielle D. Guimarães +5 more
TL;DR: This review is based on the premise that some forms of neurogenic hypertension are caused in part by the formation of angiotensin-II (Ang-II)-induced reactive oxygen species along the subfornical organ-paraventricular nucleus of the hypothalamus-rostral ventrolateral medulla pathway (SFO-PVN-RVLM pathway).
Journal ArticleDOI
Sympathoexcitatory response to peripheral chemoreflex activation is enhanced in juvenile rats exposed to chronic intermittent hypoxia.
TL;DR: Results indicate that the autonomic and respiratory responses to chemoreflex activation in juvenile rats previously submitted to CIH are greatly increased.