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Seung-Woo Lee

Researcher at Pohang University of Science and Technology

Publications -  176
Citations -  4982

Seung-Woo Lee is an academic researcher from Pohang University of Science and Technology. The author has contributed to research in topics: Cytotoxic T cell & Liquid crystal. The author has an hindex of 40, co-authored 162 publications receiving 4311 citations. Previous affiliations of Seung-Woo Lee include La Jolla Institute for Allergy and Immunology & Electronics and Telecommunications Research Institute.

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Bacterial outer membrane vesicles suppress tumor by interferon-γ-mediated antitumor response

TL;DR: Bacterial outer membrane vesicles contain immunogens but no study has yet examined their potential in treating cancer, and it is demonstrated that OMVs can suppress established tumours and prevent tumour metastasis by an interferon-γ mediated antitumor response.
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The experimental validation of a new energy harvesting system based on the wake galloping phenomenon

TL;DR: In this paper, a new energy harvesting system based on wind energy is investigated and the characteristics and mechanisms of various aerodynamic instability phenomena are first examined and the most appropriate one (i.e., wake galloping) is selected.
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Immune regulation and control of regulatory T cells by OX40 and 4-1BB

TL;DR: Recent studies of regulatory T cells, and regulatory or suppressive activity, that are modulated by OX40 or 4-1BB that suggest that there might be control by these molecules at multiple levels that will alter the biological outcome when these receptors are ligated.
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Transactivation Ability of p53 Transcriptional Activation Domain Is Directly Related to the Binding Affinity to TATA-binding Protein

TL;DR: The results suggest that at least TBP is a direct target for p53 TAD and that the binding strength of TAD to TBP (TFIID) is an important parameter controlling activity of p 53 TAD.
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Cutting Edge: CpG DNA inhibits dendritic cell apoptosis by up-regulating cellular inhibitor of apoptosis proteins through the phosphatidylinositide-3'-OH kinase pathway.

TL;DR: It is indicated that CpG DNA provides a survival signal to DCs, which might be one of mechanisms by which bacterial DNA stimulates and maintains the innate immune responses.