S
Severin Uebbing
Researcher at Yale University
Publications - 25
Citations - 1173
Severin Uebbing is an academic researcher from Yale University. The author has contributed to research in topics: Gene & Enhancer. The author has an hindex of 11, co-authored 21 publications receiving 968 citations. Previous affiliations of Severin Uebbing include Uppsala University.
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Journal ArticleDOI
The genomic landscape of species divergence in Ficedula flycatchers
Hans Ellegren,Linnéa Smeds,Reto Burri,Pall I Olason,Niclas Backström,Takeshi Kawakami,Axel Künstner,Axel Künstner,Hannu Mäkinen,Krystyna Nadachowska-Brzyska,Anna Qvarnström,Severin Uebbing,Jochen B. W. Wolf +12 more
TL;DR: This study provides a roadmap to the emerging field of speciation genomics by showing that the genomic landscape of species differentiation is highly heterogeneous with approximately 50 ‘divergence islands’ showing up to 50-fold higher sequence divergence than the genomic background.
Journal ArticleDOI
Evolutionary analysis of the female-specific avian W chromosome.
Linnéa Smeds,Vera Warmuth,Paulina Bolívar,Severin Uebbing,Reto Burri,Alexander Suh,Alexander Nater,Stanislav Bureš,László Zsolt Garamszegi,Silje Hogner,Juan Moreno,Anna Qvarnström,Milan Ružić,Stein-Are Sæther,Glenn-Peter Sætre,János Török,Hans Ellegren +16 more
TL;DR: A draft assembly of the non-recombining region of the collared flycatcher W chromosome is presented, containing 46 genes without evidence of female-specific functional differentiation, demonstrating evolutionary stable matrilineal inheritance of this nuclear–cytonuclear pair of chromosomes.
Journal ArticleDOI
Divergence in gene expression within and between two closely related flycatcher species
Severin Uebbing,Axel Künstner,Hannu Mäkinen,Niclas Backström,Paulina Bolívar,Reto Burri,Ludovic Dutoit,Carina F. Mugal,Alexander Nater,Bronwen Aken,Bronwen Aken,Paul Flicek,Fergal J. Martin,Fergal J. Martin,Stephen M. J. Searle,Hans Ellegren +15 more
TL;DR: This study of a young vertebrate speciation model system expands knowledge of how gene expression evolves as natural populations become reproductively isolated by identifying genes differentially expressed between species and finding 16 genes uniquely expressed in one of the species.
Journal ArticleDOI
Transcriptome sequencing reveals the character of incomplete dosage compensation across multiple tissues in flycatchers.
TL;DR: A model of compensation occurring on a gene-by-gene basis is supported, supported by an absence of clustering of genes on the Z chromosome with respect to the extent of compensation, which suggests male-biased expression of Z-linked genes is a derived trait after avian sex chromosome divergence.
Journal ArticleDOI
Sequencing of the needle transcriptome from Norway spruce (Picea abies Karst L.) reveals lower substitution rates, but similar selective constraints in gymnosperms and angiosperms
Jun Chen,Severin Uebbing,Niclas Gyllenstrand,Ulf Lagercrantz,Martin Lascoux,Martin Lascoux,Thomas Källman +6 more
TL;DR: A large number of single nucleotide polymorphisms as well as estimates of gene expression on transcriptome scale are yielded and the synonymous substitution rate per year is found to be an order of magnitude smaller than values reported for angiosperm herbs.