S
Sha Song
Researcher at Chinese Academy of Sciences
Publications - 6
Citations - 90
Sha Song is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Prodrug & Internal medicine. The author has an hindex of 2, co-authored 5 publications receiving 40 citations. Previous affiliations of Sha Song include Nanchang University.
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Journal ArticleDOI
Cholesterol-tuned liposomal membrane rigidity directs tumor penetration and anti-tumor effect.
Hangyi Wu,Hangyi Wu,Miaorong Yu,Yunqiu Miao,Shufang He,Zhuo Dai,Wenyi Song,Yuan Liu,Sha Song,Ejaj Ahmad,Dongkai Wang,Yong Gan +11 more
TL;DR: The results showed that liposomes with moderate rigidity gained excellent tumor penetration and enhanced anti-tumor effects, and highlight the importance of liposomal membrane rigidity.
Journal ArticleDOI
Smart Tumor Microenvironment-Responsive Nanotheranostic Agent for Effective Cancer Therapy
Shiyan Guo,Shiyan Guo,Di Sun,Dalong Ni,Miaorong Yu,Kun Qian,Wei Zhang,Yiwei Yang,Sha Song,Yang Li,Ziyue Xi,Jie Wang,Jingyi Li,Yan Wei,Kaixian Chen,Kaixian Chen,Yong Gan,Zhengtao Wang +17 more
TL;DR: In vivo pharmacodynamics results demonstrate that these synergetic effects caused by CaM‐PB NPs significantly contribute to the inhibition of tumor progression, demonstrating that theCaM‐ PB NPs with sequential theranostic functions are a promising system for effective cancer therapy.
Journal ArticleDOI
Silicone elastomer gel impregnated with 20( S )-protopanaxadiol-loaded nanostructured lipid carriers for ordered diabetic ulcer recovery
Di Sun,Shiyan Guo,Li Yang,Ya-ru Wang,Xiao-hui Wei,Sha Song,Yiwei Yang,Yong Gan,Zhengtao Wang +8 more
TL;DR: It is demonstrated that the developed PPD-NS could facilitate ordered diabetic wound recovery via multifunctional improvement during different wound-healing phases through suppressing inflammatory infiltration in the inflammatory phase, promoting angiogenesis during the proliferation phase, and regulating collagen deposition in the remodeling phase.
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Enzyme-Activated Prodrug-Based Smart Liposomes Specifically Enhance Tumor Hemoperfusion with Efficient Drug Delivery to Pancreatic Cancer Cells and Stellate Cells
Nianxiu Duan,Nianxiu Duan,Nianxiu Duan,Junjun Li,Junjun Li,Sha Song,Sha Song,Feng Wang,Yiwei Yang,Di Nie,Caifen Wang,Yingjie Sheng,Yali Tao,Jie Gao,Can Xu,Yan Wei,Yan Wei,Yong Gan +17 more
TL;DR: By enhancing the exposure of DOX and CAL to tumor cells and aPSCs, respectively, in a tumor‐specific manner, MR‐T‐PD exerts superior efficacy without causing additional side effects, and represents a promising paradigm for pancreatic cancer therapy.
Journal ArticleDOI
Transfersomes improved delivery of ascorbic palmitate into the viable epidermis for enhanced treatment of melasma.
Junjun Li,Nianxiu Duan,Sha Song,Di Nie,Miaorong Yu,Jie Wang,Ziyue Xi,Jingyi Li,Yingjie Sheng,Can Xu,Yan Wei,Yong Gan +11 more
TL;DR: Ascorbic palmitate (AP) was encapsulated into the transfersomes (TFs), yielding AP-TFs, which utilized the deformability of TFs to squeeze through the skin pores in the stratum corneum under the transepidermal hydration gradient forces, leading to 14.1-fold increase in AP accumulation to the viable epidermis (EP).