Shannon L. Russell

TL;DR: The advances in modeling and analysis of gut microbiota will further the authors' knowledge of their role in health and disease, allowing customization of existing and future therapeutic and prophylactic modalities.

TL;DR: It is reported in a longitudinal human study that infants at risk of asthma have transient gut microbial dysbiosis during the first 100 days of life, and certain bacterial genera were decreased in these children, suggesting a potential causative role of the loss of these microbes.

TL;DR: Data support a neonatal, microbiota‐driven, specific increase in susceptibility to experimental murine allergic asthma, consistent with the ‘hygiene hypothesis’.

TL;DR: A better understanding of both the changes in the microbiota as a result of antibiotic treatment and the consequential changes in host immune homeostasis is imperative, so that these effects can be mitigated.

TL;DR: It is suggested that antibiotic perturbation of the microbiota can disrupt intestinal homeostasis and the integrity of intestinal defenses, which protect against invading pathogens and intestinal inflammation.