Marta Wlodarska

TL;DR: A comprehensive review highlights recent advances in understanding of the intestinal pathotypes of E. coli, which carry an enormous potential to cause disease and continue to present challenges to human health.

TL;DR: Data support a neonatal, microbiota‐driven, specific increase in susceptibility to experimental murine allergic asthma, consistent with the ‘hygiene hypothesis’.

TL;DR: It is demonstrated that the NLRP6 inflammasome, a recently described regulator of colonic microbiota composition and biogeographical distribution, is a critical orchestrator of goblet cell mucin granule exocytosis, linking nonhematopoietic inflammaome signaling to autophagy and highlighting the gobleT cell as a critical innate immune player in the control of intestinal host-microbial mutualism.

TL;DR: It is suggested that antibiotic perturbation of the microbiota can disrupt intestinal homeostasis and the integrity of intestinal defenses, which protect against invading pathogens and intestinal inflammation.

TL;DR: It is demonstrated that early-life consumption of a moderately malnourished diet, in combination with iterative oral exposure to commensal Bacteroidales species and Escherichia coli, remodels the murine small intestine to resemble features of EE observed in humans.