S
Sharon X. Xie
Researcher at University of Pennsylvania
Publications - 230
Citations - 18360
Sharon X. Xie is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Dementia & Cognitive decline. The author has an hindex of 66, co-authored 211 publications receiving 15092 citations. Previous affiliations of Sharon X. Xie include Pennsylvania State University & Leonard Davis Institute of Health Economics.
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Journal ArticleDOI
Validity of the MoCA and MMSE in the detection of MCI and dementia in Parkinson disease
Staci Hoops,Sarra Nazem,Andrew Siderowf,John E. Duda,Sharon X. Xie,M.B. Stern,Daniel Weintraub +6 more
TL;DR: The Montreal Cognitive Assessment has adequate psychometric properties as a screening instrument for the detection of mild cognitive impairment or dementia in Parkinson disease, however, a positive screen using either instrument requires additional assessment due to suboptimal specificity at the recommended screening cutoff point.
Journal ArticleDOI
Cognitive therapy for the prevention of suicide attempts: a randomized controlled trial.
Gregory K. Brown,Thomas R. Ten Have,Gregg Henriques,Sharon X. Xie,Judd E. Hollander,Aaron T. Beck +5 more
TL;DR: Cognitive therapy was effective in preventing suicide attempts for adults who recently attempted suicide and reported significantly less hopelessness than the usual care group at 6 months and 18 months.
Cognitive Therapy for the Prevention of Suicide Attempts
TL;DR: In this article, the authors evaluated the effectiveness of a 10-session cognitive therapy inter-vention designed to prevent repeated suicide attempts in a randomized controlled trial of 120 individuals who attempted suicide and were evaluated at a hospital emergency department within 48 hours of the attempt.
Journal ArticleDOI
Contribution of cerebrovascular disease in autopsy confirmed neurodegenerative disease cases in the National Alzheimer’s Coordinating Centre
Jon B. Toledo,Steven E. Arnold,Kevin M. Raible,Johannes Brettschneider,Sharon X. Xie,Murray Grossman,Sarah E. Monsell,Walter A. Kukull,John Q. Trojanowski +8 more
TL;DR: Concurrent cerebrovascular disease is a common neuropathological finding in aged subjects with dementia, is more common in Alzheimer's disease than in other neurodegenerative disorders, especially in younger subjects, and lowers the threshold for dementia due to Alzheimer’s disease and α-synucleinopathies, which suggests that these disorders should be targeted by treatments for cerebroVascular disease.
Journal ArticleDOI
Neuropathologic substrates of Parkinson disease dementia.
David J. Irwin,Matthew T. White,Jon B. Toledo,Sharon X. Xie,John L. Robinson,Vivianna M. Van Deerlin,Virginia M.-Y. Lee,James B. Leverenz,Thomas J. Montine,John E. Duda,Howard I. Hurtig,John Q. Trojanowski +11 more
TL;DR: A study was undertaken to examine the neuropathological substrates of cognitive dysfunction and dementia in Parkinson disease (PD).