Sharona Even-Ram

TL;DR: Analysis of the different modes of migration of cells in matrices provides new insights, but also raises some debates about the mechanisms and regulation of cell migration in three-dimensional matrices.

TL;DR: Total Rac1 activity can provide a regulatory switch between patterns of cell migration by a mechanism distinct from chemotaxis, and be used to determine whether cell patterns of migration are intrinsically random or directionally persistent.

TL;DR: It is concluded that myosin IIA negatively regulates cell migration and it is suggested that it maintains a balance between the actomyosin and microtubules systems by regulating microtubule dynamics.

TL;DR: It is demonstrated that nicotinamide promotes the differentiation of hESCs to neural and subsequently to RPE fate and factors from the TGF-beta superfamily, which presumably pattern RPE development during embryogenesis, further direct RPE differentiation.

TL;DR: Thrombin receptor, a member of the protease-activated receptor family, is preferentially expressed in highly metastatic human breast carcinomas cell lines and breast carcinoma biopsy specimens and introduction of thrombin receptors antisense cDNA considerably inhibited the invasion of metastatic breast carcin cancer cells in culture through a reconstituted basement membrane.