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Eyal Banin
Researcher at Hebrew University of Jerusalem
Publications - 207
Citations - 8270
Eyal Banin is an academic researcher from Hebrew University of Jerusalem. The author has contributed to research in topics: Retinitis pigmentosa & Retinal degeneration. The author has an hindex of 46, co-authored 191 publications receiving 7236 citations. Previous affiliations of Eyal Banin include University of Pennsylvania & Scripps Research Institute.
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Directed Differentiation of Human Embryonic Stem Cells into Functional Retinal Pigment Epithelium Cells
Maria Idelson,Ruslana Alper,Alexey Obolensky,Etti Ben-Shushan,Itzhak Hemo,Nurit Yachimovich-Cohen,Hanita Khaner,Yoav Smith,Ofer Wiser,Michal Gropp,Malkiel A. Cohen,Sharona Even-Ram,Yael Berman-Zaken,Limor Matzrafi,Gideon Rechavi,Eyal Banin,Benjamin Reubinoff +16 more
TL;DR: It is demonstrated that nicotinamide promotes the differentiation of hESCs to neural and subsequently to RPE fate and factors from the TGF-beta superfamily, which presumably pattern RPE development during embryogenesis, further direct RPE differentiation.
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Hypomorphic mutations in syndromic encephalocele genes are associated with Bardet-Biedl syndrome
Carmen C. Leitch,Norann A. Zaghloul,Erica E. Davis,Corinne Stoetzel,Anna Diaz-Font,Suzanne Rix,Majid Alfadhel,Richard A. Lewis,Wafaa Eyaid,Eyal Banin,Hélène Dollfus,Philip L. Beales,Jose L. Badano,Jose L. Badano,Nicholas Katsanis +14 more
TL;DR: Hypomorphic mutations in syndromic encephalocele genes are associated with Bardet-Biedl syndrome as discussed by the authors, which is a type of hereditary encephalopathy.
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Rescue of retinal degeneration by intravitreally injected adult bone marrow–derived lineage-negative hematopoietic stem cells
Atsushi Otani,Michael I. Dorrell,Karen Kinder,Stacey K. Moreno,Steven Nusinowitz,Eyal Banin,John R. Heckenlively,Martin Friedlander +7 more
TL;DR: It is demonstrated that whenever a fraction of mouse or human adult bone marrow-derived stem cells (lineage-negative hematopoietic stem cells [Lin- HSCs] containing endothelial precursors stabilizes and rescues retinal blood vessels that would ordinarily completely degenerate, a dramatic neurotrophic rescue effect is also observed.
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Genetically engineered large animal model for studying cone photoreceptor survival and degeneration in retinitis pigmentosa
Robert M. Petters,Alexander Ca,Kevin D. Wells,E. B. Collins,Sommer,Blanton Mr,Rojas G,Hao Y,W. L. Flowers,Eyal Banin,Artur V. Cideciyan,Samuel G. Jacobson,Fulton Wong +12 more
TL;DR: These transgenic pigs that express a mutated rhodopsin gene will provide a large animal model for study of the protracted phase of cone degeneration found in RP and for preclinical treatment trials.
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Myeloid progenitors differentiate into microglia and promote vascular repair in a model of ischemic retinopathy
Matthew R. Ritter,Eyal Banin,Stacey K. Moreno,Edith Aguilar,Michael I. Dorrell,Martin Friedlander +5 more
TL;DR: Using a model of oxygen-induced retinopathy, it is demonstrated that a population of adult BM-derived myeloid progenitor cells migrated to avascular regions of the retina, differentiated into microglia, and facilitated normalization of the vasculature.