S
Shawn Trojahn
Researcher at Washington State University
Publications - 5
Citations - 72
Shawn Trojahn is an academic researcher from Washington State University. The author has contributed to research in topics: Hibernation & Gene. The author has an hindex of 2, co-authored 4 publications receiving 39 citations.
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Journal ArticleDOI
Hibernation induces widespread transcriptional remodeling in metabolic tissues of the grizzly bear.
Heiko T. Jansen,Shawn Trojahn,Michael W. Saxton,Corey R. Quackenbush,Brandon D. Evans Hutzenbiler,O. Lynne Nelson,Omar E. Cornejo,Charles T. Robbins,Joanna L. Kelley +8 more
TL;DR: It is found that during hibernation, adipose tissue has the largest number of differentially expressed genes of the three tissues examined, revealing potential therapeutic targets for human diseases.
Journal ArticleDOI
Whole-genome sequencing reveals the extent of heterozygosity in a preferentially self-fertilizing hermaphroditic vertebrate.
Luana S. F. Lins,Shawn Trojahn,Alexandra Sockell,Muh-Ching Yee,Andrey Tatarenkov,Carlos Bustamante,Ryan L. Earley,Joanna L. Kelley +7 more
TL;DR: This study used whole-genome data to assess the levels of heterozygosity in different lineages of the mangrove rivulus and infer the phylogenetic relationships among those lineages, and sequenced whole genomes from 15 lineages that were completely homozygous at microsatellite loci.
Journal ArticleDOI
Author Correction: Hibernation induces widespread transcriptional remodeling in metabolic tissues of the grizzly bear.
Heiko T. Jansen,Shawn Trojahn,Michael W. Saxton,Corey R. Quackenbush,Brandon D. Evans Hutzenbiler,O. Lynne Nelson,Omar E. Cornejo,Charles T. Robbins,Joanna L. Kelley +8 more
TL;DR: An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Posted ContentDOI
Long-read isoform sequencing reveals tissue-specific isoform expression between active and hibernating brown bears (Ursus arctos)
Tseng E,Jason G. Underwood,Evans Hutzenbiler Bd,Shawn Trojahn,Kingham B,Shevchenko O,Bernberg E,Charles T. Robbins,Heiko T. Jansen,Joanna L. Kelley +9 more
TL;DR: In this article, the role of differential expression of gene isoforms on hibernation physiology was studied in brown bears and it was shown that differential isoform usage is an important mechanism for modulating genes during hibernation.
Journal ArticleDOI
Serum plays an important role in reprogramming the seasonal transcriptional profile of brown bear adipocytes
Michael W. Saxton,Blair W. Perry,B. D. Evans Hutzenbiler,Shawn Trojahn,Alexia Gee,Anthony P. Brown,Gennifer E. Merrihew,Jea-Woo Park,Omar E. Cornejo,Michael J. MacCoss,Charles T. Robbins,Heiko T. Jansen,Joanna L. Kelley +12 more
TL;DR: This article performed RNA-sequencing on brown bear adipocytes and proteomics on serum to identify changes possibly responsible for reversible insulin resistance in hibernation and observed dramatic transcriptional changes, which depended on both the cell and serum season of origin.