Sheila K. Singh

TL;DR: Tumor transformation was associated with overexpression of components of the sonic hedgehog and Wnt developmental signaling pathways, which are known to regulate tumor-initiating cells in malignant brain neoplasms.

TL;DR: Current evidence for the presence of interventions to manage obesity, including hypothalamic obesity, in SCBT is summarized.

TL;DR: It is shown that RAD51 expression, foci formation and homologous recombination repair activity are unaltered in normal and tumorigenic PTEN-deficient cells and patient samples, underscoring a need to discontinue its use in treating patients with PTEN -deficient tumors that do not otherwise exhibit HRD.

TL;DR: Light is shed on the association of three genes with CD133-BMI1 circuitry, their importance as downstream effectors of the BMI1 signalling pathway, and their potential as future targets for tackling GBM treatment-resistant cell populations.

TL;DR: In this article, the authors examined the association between endovascular mechanical thrombectomy and clinical outcomes among patients with acute ischemic stroke, including functional independence at 90 days, functional independence (mRS score, 0-2), angiographic revascularization, symptomatic intracranial hemorrhage within 90 days and all-cause mortality at