Sheng-Li Cao

TL;DR: A series of 4(3H)-quinazolinone derivatives with dithiocarbamate side chains were synthesized and tested for their in vitro antitumor activity against human myelogenous leukemia K562 cells, and Piperazine-1-carbodithioate 8q exhibited significant inhibitory activity.

TL;DR: A first methylthio-functionalized porous MOF decorated with Pt co-catalyst for efficient photocatalytic H2 evolution was achieved, which exhibited a high quantum yield and perfect H2 production rate.

TL;DR: For the first time, group-specific PAE-binding aptamers via rationally designed target immobilization are identified and offered the promise of convenient, low-cost detection of total PAEs.

TL;DR: Investigations revealed that compounds 8f, 8m and 8q exhibited weak inhibition against dihydrofolate reductase and no activity against thymidylate synthase, while induced DNA damage and activated the G2/M checkpoint in HCT-116 cells.

TL;DR: A series of indolin-2-one derivatives bearing 4-phenylpiperazine-1-carbothiohydrazide moiety at the C3-position were synthesized and evaluated for their antiproliferative activity against three human cancer cell lines.