S
Sheng Lin
Researcher at Hong Kong Baptist University
Publications - 38
Citations - 1512
Sheng Lin is an academic researcher from Hong Kong Baptist University. The author has contributed to research in topics: Virtual screening & Pharmacophore. The author has an hindex of 21, co-authored 38 publications receiving 1330 citations. Previous affiliations of Sheng Lin include University of Macau.
Papers
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Journal ArticleDOI
Luminescence switch-on detection of protein tyrosine kinase-7 using a G-quadruplex-selective probe
Sheng Lin,Wei Gao,Zeru Tian,Chao Yang,Lihua Lu,Jean-Louis Mergny,Jean-Louis Mergny,Chung-Hang Leung,Dik-Lung Ma +8 more
TL;DR: A novel luminescent G-quadruplex-selective iridium(iii) complex was employed in a G- quadruplex -based detection assay for PTK7.
Journal ArticleDOI
Luminescent chemosensors by using cyclometalated iridium(iii) complexes and their applications.
TL;DR: This review describes recent examples of cyclometalated iridium(iii) metal complexes that act as luminescent chemosensors for cations, anions or small molecules.
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Label-free luminescence switch-on detection of hepatitis C virus NS3 helicase activity using a G-quadruplex-selective probe
Ka-Ho Leung,Hong-Zhang He,Bingyong He,Hai-Jing Zhong,Sheng Lin,Yitao Wang,Dik-Lung Ma,Chung-Hang Leung +7 more
TL;DR: A novel luminescent G- quadruplex-selective iridium(iii) complex was employed in a label-free G-quadruplex -based detection assay for hepatitis C virus NS3 helicase activity.
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Inhibition of the Ras/Raf interaction and repression of renal cancer xenografts in vivo by an enantiomeric iridium(iii) metal-based compound.
Li-Juan Liu,Wanhe Wang,Shi-Ying Huang,Yanjun Hong,Guodong Li,Sheng Lin,Jinglin Tian,Zongwei Cai,Hui-Min David Wang,Dik-Lung Ma,Chung-Hang Leung +10 more
TL;DR: This study reports the first use of an iridium(iii) compound and its enantiomer to inhibit the H-Ras/Raf-I PPI in vitro and repress renal cancer xenografts in vivo.
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Metal complexes as potential modulators of inflammatory and autoimmune responses
TL;DR: In this perspective, recent examples in the development of transition metal complexes as modulators of inflammatory and autoimmune responses are highlighted.