S
Shengbin Zhou
Researcher at Chinese Academy of Sciences
Publications - 45
Citations - 734
Shengbin Zhou is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Enantioselective synthesis & Amino acid. The author has an hindex of 14, co-authored 41 publications receiving 653 citations. Previous affiliations of Shengbin Zhou include Stony Brook University.
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Journal ArticleDOI
Ruthenium-Catalyzed Redox-Neutral [4 + 1] Annulation of Benzamides and Propargyl Alcohols via C–H Bond Activation
TL;DR: In this paper, the authors report ruthenium(II)-catalyzed redox-neutral annulation of benzamides and propargyl alcohols, in which propargy alcohols act as one-carbon units.
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Chemical kinetic resolution of unprotected β-substituted β-amino acids using recyclable chiral ligands.
Shengbin Zhou,Jiang Wang,Xia Chen,José Luis Aceña,Vadim A. Soloshonok,Vadim A. Soloshonok,Hong Liu +6 more
TL;DR: The first chemical method for resolution of N,C-unprotected β-amino acids was developed through enantioselective formation and disassembly of nickel(II) complexes under operationally convenient conditions to prepare the anti-diabetic drug sitagliptin.
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Asymmetric total synthesis and identification of tetrahydroprotoberberine derivatives as new antipsychotic agents possessing a dopamine D1, D2 and serotonin 5-HT1A multi-action profile
Haifeng Sun,Liyuan Zhu,Huicui Yang,Wangke Qian,Lin Guo,Shengbin Zhou,Bo Gao,Zeng Li,Yu Zhou,Hualiang Jiang,Kaixian Chen,Xuechu Zhen,Xuechu Zhen,Hong Liu +13 more
TL;DR: The results suggest that these two THPBs compounds targeted to multiple neurotransmitter receptors may present novel lead drugs with new pharmacological profiles for the treatment of schizophrenia.
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Recyclable Ligands for the Non-Enzymatic Dynamic Kinetic Resolution of Challenging α-Amino Acids.
Nian Yong,Nian Yong,Jiang Wang,Shengbin Zhou,Shuni Wang,Hiroki Moriwaki,Aki Kawashima,Vadim A. Soloshonok,Vadim A. Soloshonok,Hong Liu,Hong Liu +10 more
TL;DR: Structurally simple and inexpensive chiral tridentate ligands were employed for substantially advancing the purely chemical dynamic kinetic resolution of unprotected racemic tailor-made α-amino acids, enabling the first DKR of TM-α-AAs bearing tertiary alkyl chains as well as multiple unprotected functional groups.
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Asymmetric Synthesis of Sterically and Electronically Demanding Linear ω-Trifluoromethyl Containing Amino Acids via Alkylation of Chiral Equivalents of Nucleophilic Glycine and Alanine
TL;DR: An operationally convenient, scalable asymmetric synthesis of linear, ω-trifluoromethyl-containing amino acids, which were not previously produced in their enantiomerically pure form, has been developed via alkylation of chiral equivalents of nucleophilic glycine and alanine.