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Shengxing Wang
Researcher at Chinese Academy of Sciences
Publications - 5
Citations - 516
Shengxing Wang is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Genome editing & Gene. The author has an hindex of 2, co-authored 3 publications receiving 256 citations.
Papers
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Journal ArticleDOI
Prime genome editing in rice and wheat
Qiupeng Lin,Yuan Zong,Chenxiao Xue,Shengxing Wang,Shuai Jin,Zixu Zhu,Yanpeng Wang,Andrew V. Anzalone,Andrew V. Anzalone,Andrew V. Anzalone,Aditya Raguram,Aditya Raguram,Aditya Raguram,Jordan L. Doman,Jordan L. Doman,Jordan L. Doman,David R. Liu,David R. Liu,David R. Liu,Caixia Gao +19 more
TL;DR: The resulting suite of plant prime editors enable point mutations, insertions and deletions in rice and wheat protoplasts through codon, promoter, and editing-condition optimization.
Journal ArticleDOI
Precise, predictable multi-nucleotide deletions in rice and wheat using APOBEC-Cas9.
Shengxing Wang,Yuan Zong,Qiupeng Lin,Huawei Zhang,Zhuangzhuang Chai,Dandan Zhang,Kunling Chen,Jin-Long Qiu,Caixia Gao +8 more
TL;DR: A series of APOBEC–Cas9 fusion-induced deletion systems (AFIDs) that combine Cas9 with human APOBec3A (A3A), uracil DNA-glucosidase and apurinic or apyrimidinic site lyase are reported, which could be applied to study regulatory regions and protein domains to improve crop plants.
Journal ArticleDOI
Antagonistic control of seed dormancy in rice by two bHLH transcription factors
Fan Xu,Jiuyou Tang,Shengxing Wang,Xi Cheng,Hongru Wang,Shujun Ou,Shaopei Gao,Boshu Li,Yangwen Qian,Caixia Gao,Chengcai Chu +10 more
Journal ArticleDOI
A precise and efficient adenine base editor.
Tianxiang Tu,Zongming Song,Xiaoyu Liu,Shengxing Wang,Xiaoxue He,Haitao Xi,Jiahua Wang,Tong Yan,Haoran Chen,Zhenwu Zhang,Xiujuan Lv,Jineng Lv,Xiufeng Huang,Junzhao Zhao,Chao-Po Lin,Caixia Gao,Jinwei Zhang,Feng Gu +17 more
TL;DR: In this article , NG-ABE9e exhibits robust and precise base-editing activity in human cells, with more than 7-fold bystander editing reduction at some sites.
Patent
Improved gene editing system
TL;DR: In this paper, a gene editing system for editing a target sequence in the genome of a cell, comprising a CRISPR nuclease, a cytosine deaminase, an AP lyase, a guide RNA and optionally an uracil-DNA glycosylase.