Shijun Sun

TL;DR: It is revealed that fitness advantage of ST59-t437- MRSA over ST239-t030-MRSA may lead to changes in genetic structure and increased susceptibility of MRSA to rifampicin and fluoroquinolones in Chinese patients with S. aureus bacteremia.

TL;DR: A plasmid-mediated tigecycline resistance mechanism, a 6,489 bp Resistance-nodulation-division family (RND) efflux pump (tmexCD1-toprJ1 pump), that confers transferable tigECyclines resistance in K pneumoniae isolated from patients and chickens is reported.

TL;DR: The authors in this article developed a computational approach to track structural variants surrounding blaNDM, which allows them to identify prevalent genomic contexts, mobile genetic elements, and likely events in the gene's global spread.

TL;DR: In this paper, the authors used three control groups (external negative controls under long-term surveillance, blood samples with a negative result in conventional tests, and a group of healthy people) to distinguish contaminants arising from specimen collection, sample processing, and human normal flora.

TL;DR: The severity of illness, meropenem MICs of >8 mg/liter, and carbapenemase-producing types were associated with the clinical outcome and survival analysis revealed appropriate therapy was associated with a lower 14-day mortality rate than inappropriate therapy, and combination therapy was superior to monotherapy.